Study programme competencies |
Code
|
Study programme competences
|
A3 |
Skills of using usual techniques and instruments in the cellular, biological and molecular research: that are able to use techniques and instruments as well as understanding potentials of their uses and applications. |
A4 |
Skills of working in a sure way in the laboratories knowing operation handbooks and actions to avoid incidents of risk. |
A8 |
Skills of having an integrated view of the previously acquired knowledge about Molecular and Cellular Biology and Genetics, with an interdisciplinary approach and experimental work. |
A16 |
Skills of understanding the microorganisms' role as pathogenic agents and as biotechnological tools. |
A18 |
Skills to become a professional in health, pharmacy, veterinary, animal production, biotechnology or food sectors |
B1 |
Analysis skills to understand biological problems in connection with the Molecular and Cellular Biology and Genetics. |
B2 |
Skills of management of the information: that are able to gather and to understand relevant information and results, obtaining conclusions and to prepare reasoned reports on scientific and biotechnological questions. |
B3 |
Skills of decision making for the problem solving: that are able to apply theoretical knowledges and practical acquired in the formulation of biological problems and the looking for solutions. |
B4 |
Organization and work planning skills: that are able to manage the use of the time as well as available resources and to organize the work in the laboratory. |
B5 |
Correct oral and written communication on scientific topics in the native language and at least in another International diffusion language. |
B7 |
Personal progress skills : that are able to learn from freelance way, adapting to new situations, developing necessary qualities as the creativity, skills of leadership, motivation for the excellence and the quality. |
B8 |
Critical reasoning skills and ethical commitment with the society: sensitivity in front of bioethical problems and to the ones related to the natural resource conservation |
B9 |
Skills of preparation, show and defense of a work. |
C3 |
Skills of Using basic tools of the information technologies and communications (ICT) necessary to the exercise of his profession and for the apprenticeship over his life. |
C4 |
Skills of take place for the exercise of an open citizenship, highbrow, critic, committed, democratic and solidary, able to analyze the reality, diagnosing problems, formulating and to implement solutions based on the knowledge and oriented to common good. |
C5 |
Understanding the importance of the enterprising culture and to know means within reach of enterprising people. |
C6 |
Considering critically the knowledge, technologies and the available information to solve problems with which should face. |
C7 |
Assuming as a professional and citizen the importance of the apprenticeship over the life. |
C8 |
Considering the importance that the investigation has, the innovation and the technological development in the socioeconomic advance and cultural of the society. |
Learning aims |
Subject competencies (Learning outcomes) |
Study programme competences |
Understand the microbial cooperative behavior and the interactions of micro-organisms with other living beings at the molecular level |
AR5 AR12 AR13
|
BR5 BR7 BR8
|
CC6 CC7 CC8
|
Handle the techniques and understand the molecular basis of the fight against infections and resistance mechanisms
|
AR1 AR2 AR12 AR13
|
BR1
|
CC4 CC7 CC8
|
Apply the molecular knowledge to understanding and solving problems |
AR5 AR12 AR13
|
BR1 BR2 BR3 BR4 BR7 BR8 BR9
|
CC3 CC4 CC5 CC6 CC7 CC8
|
Contents |
Topic |
Sub-topic |
Microbial cooperative behaviour
|
-Molecular basis for the cooperation
-Practical implications |
Microbial interactions |
-Positive and negative interactions
-Molecular basis of the interactions with other microorganisms, plants or animals
|
Biotechnological applications |
-Practical aplications of the microbial molecular interactions |
Mechanisms of resistance to antimicrobial agents |
-Enzymes degrading antimicrobial agents
-Expulsion pumps
-Modification of targets
-Regulation of porins
|
Practical study of different aspects involved in the resistance to antimicrobial agents |
-PCR of involved genes
-Gene clonning
-Protein expression
-Preparation of knock-out mutants
-Studies of the regulation of the mechanisms of resistance through RNA analysis |
Planning |
Methodologies / tests |
Ordinary class hours |
Student’s personal work hours |
Total hours |
Short answer questions |
1 |
0 |
1 |
Guest lecture / keynote speech |
8 |
16 |
24 |
Laboratory practice |
24 |
12 |
36 |
Seminar |
2 |
10 |
12 |
|
Personalized attention |
2 |
0 |
2 |
|
(*)The information in the planning table is for guidance only and does not take into account the heterogeneity of the students. |
Methodologies |
Methodologies |
Description |
Short answer questions |
Written test that will assess the grade of knowledge and understanding achieved by the student. |
Guest lecture / keynote speech |
Exposure by the teaching staff of the theoretical basis of the subject |
Laboratory practice |
Case study in the research laboratory of dfferent aspects involved in resistance to antimicrobial agents carried out by the students. |
Seminar |
Working Group that will discuss certain aspects related to the subject, elaborating final conclusions |
Personalized attention |
Methodologies
|
Guest lecture / keynote speech |
Laboratory practice |
Seminar |
|
Description |
During the development of the subject will be addressed in the needs of the student and consultations relating to the subject matter, providing you the necessary support, both in person or through email.
Durante el desarrollo de la asignatura se atenderá a las necesidades y consultas del alumno relacionadas con la materia, proporcionándole la orientación y el apoyo que sea necesario, tanto de forma presencial o no presencial (fundamentalmente a través del correo electrónico).
|
|
Assessment |
Methodologies
|
Description
|
Qualification
|
Laboratory practice |
Continuous assessment of practices |
25 |
Seminar |
Active participation in the programmed seminars |
5 |
Short answer questions |
Written test on the knowledge acquired during the course, both in its theoretical and practical aspects |
70 |
|
Assessment comments |
|
Sources of information |
Basic
|
Gerischer (Ed) (2008). Acinetobacter Molecular Biology. Caister Academic Press
Madigan, Martinko, Dunlap & Clark (2009). Brock. Biología de los microorganismos. 12ª edición. Madrid. Pearson Educación, S.A.
Lederberg & Schaeter (Eds) (2009). Encyclopedia of Microbiology. 3rd edition. Academic Press |
|
Complementary
|
Otero, Muñoz, Bernárdez & Fábregas (2005). "Quorum sensing": El lenguaje de las bacterias. Zaragoza. Acribia
Maragakis & Perl (2008). Acinetobacter baumannii: epidemiology, antimicrobial resistance, and treatment options. Clin Infect Dis 46(8): 1254-63
Vila, Martí & Sánchez-Céspedes (2007). Porins, efflux pumps and multidrug resistance in Acinetobacter baumannii. J Antimicrob Chemother 59(6): 1210-5
Gootz (2010). The global problem of antibiotic resistance. Crit Rev Inmunol 30(1): 79-93
Pachón & Vila (2009). Treatment of multiresistant Acinetobacter baumannii infections. Curr Opin Invest Drugs 10(2): 150-6 |
It is noted here several revisions directly related to the content of the subject. In addition, during the development of the subject the student is given another bibliography, depending on the scheduled seminars and any other developments that arose. |
Recommendations |
Subjects that it is recommended to have taken before |
Técnicas Celulares/610441001 | Técnicas Moleculares/610441002 | Bioloxía Celular Avanzada/610441003 | Señalización Celular/610441004 | Mecanismos de xeración da variación xenética/610441005 | Regulación da expresión xénica/610441006 |
|
Subjects that are recommended to be taken simultaneously |
|
Subjects that continue the syllabus |
Regulación da expresión xénica/610441006 | Mecanismos Moleculares da Interacción Planta-patóxeno/610441018 |
|
Other comments |
Of all the subjects that it recommends to have studied previously, compulsory all of them of the master's degree, the technical subjects are considered to be fundamental |
|