Mestrado Universitario en Bioloxía Molecular , Celular e Xenética |
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Identifying Data | 2014/15 | |||||||||||||
Subject | Toxicología Xenética | Code | 610441017 | |||||||||||
Study programme |
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Descriptors | Cycle | Period | Year | Type | Credits | |||||||||
Official Master's Degree | 2nd four-month period |
First | Optativa | 3 | ||||||||||
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Basic | |
BOOKS: Klaassen, C.D.; Watkins III, J.B. (2005) Fundamentos de Toxicología de Casarett y Doull. Madrid: MacGraw Hill. Marquardt, H. ; Schäfer, S.G.; McClellan, R.O.; Welsch, F. (1999) Toxicology. Repetto, M.; Repetto, G. (2009) Toxicología fundamental. Madrid: Díaz de Santos. Riviere, J.E. (2006) Biological concepts and Techniques in Toxicology. An integrated approach. Stine, K.E; Brown, T.M. (2006) Principles of toxicology. 2nd edition. Londres: CRC Press Taylor & Francis. ARTICLES: Benigni, R.; Battistelli, C.L.; Bossa, C.; Tcheremenskaia, O.; Crettaz, P. (2013) New perspectives in toxicological information management, and the role of isstox databases in assessing chemical mutagenicity and carcinogenicity. Mutagenesis 28: 401-409. Cimino, M. C. 2006. Comparative overview of current international strategies and guidelines for genetic toxicology testing for regulatory purposes. Environmental and Molecular Mutagenesis 47:362-390. Gallo, V.; Khan, A.; Gonzales, C.; Phillips, D.H.; Schoket, B.; Györffy, E.; Anna, L.; Kovács, K.; Moller, P.; Loft, S.; Kyrtopoulos, S.; Matullo, G.; Vineis, P. (2008) Validation of biomarkers for the study of environmental carcinogens: A review. Biomarkers 13: 505 - 534. Imyanitov, E.N.; Srám, R.J. y Binková, B. (2000) Molecular epidemiology studies on occupational and environmental exposure to mutagens and carcinogens, 1997-1999. Environ. Health Perspect.108: 57-70. Young, R. 2002. Genetic toxicology: Web resources. Toxicology 173:103-121. |
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Complementary | |
BOOKS: Barile, F.A. (2008) Principles of Toxicology Testing. Florida: CRC Press. Córdoba, D. (2001) Toxicología. Bogotá: Manual Moderno. DeCaprio, A. (2006) Toxicologic biomarkers. Hamadeh, H.K.; Hodgson, E.; Levi, P.E. (1997) A textbook of modern toxicology. IPCS (1993) Biomarkers and risk assessment: concepts and principles. International Programme on chemical safety. Environmental Health Criteria 155. World Health Organization. Mendelsohn, M.L.; Mohr, L.C.; Peeters, J.P. (1998) Biomarkers. Medical and workplace applications. Mendelsohn, M.L.; Peeters, J.P.; National Research Council of the National Academies (2006) Human biomonitoring for environmental chemicals. Niesink, R.J.M. (1996) Toxicology: principles and applications. Boca Raton-Florida: CRC Press. Repetto, M. (1995) Toxicología avanzada. Madrid: Díaz de Santos. Albertini, R.J.; Nicklas, J.A.; O'Neill, J.P. (1996) Future research directions for evaluating human genetic and cancer risk from environmental exposures. Environ. Health Perspect104 (Suppl 3): 503-510. Au, W.W.; Oh, H.Y.; Grady, J.; Salama, S.A. y Heo, M.Y. (2001) Usefulness of genetic susceptibility and biomarkers for evaluation of environmental health risk. Environ. Mol. Mutagen.37: 215-225. Autrup, H. (2000) Genetic polymorphisms in human xenobiotica metabolizing enzymes as susceptibility factors in toxic response. Mutat. Res.464: 65-76. Bonassi, S. (1999) Combining environmental exposure and genetic effect measurements in health outcome assessment. Mutat. Res.428: 177-185. Butterworth, B.E.; Bogdanffy, M.S. (1999) A comprehensive approach for integration of toxicity and cancer risk assessments. Regul. Toxicol. Pharmacol.29: 23-36. Garte, S. (2001) Metabolic susceptibility genes as cancer risk factors: time for a reassessment? Cancer Epidemiol. Biomarkers Prev.10: 1233-1237. Gyorffy, E., Anna, L., Kovacs, K., Rudnai, P., and Schoket, B. (2008) Correlation between biomarkers of human exposure to genotoxins with focus on carcinogen-DNA adducts. Mutagenesis 23:1-18. Ingelman-Sundberg, M. (2001) Genetic variability in susceptibility and response to toxicants. Toxicol. Lett.120: 259-268. Lang, M. y Pelkonen, O. (1999) Metabolism of xenobiotic and chemical carcinogenesis. Metabolic polymorphisms and susceptibility to cancer. IARC Scientific Publications No. 148.International Agency for Research on Cancer. Norppa, H. (2001) Genetic polymorphisms and chromosome damage. Int. J. Hyg. Environ. Health204: 31-38. Pavanello, S. (2003) Metabolic and DNA repair variations in susceptibility to genotoxins. Polycyclic Aromatic Compounds Pavanello, S. y Clonfero, E. (2000) Biological indicators of genotoxic risk and metabolic polymorphisms. Mutat. Res.463: 285-308. Pavanello, S.; Lotti, M. (2012) Biological monitoring of carcinogens: Current status and perspectives. Archives of Toxicology 86: 535-541. Seidegard, J. y Ekström, G. (1997) The role of human glutathione transferases and epoxide hydrolases in the metabolism of xenobiotics. Environ. Health Perspect.105: 791-799. Schulte, P.A.; Hauser, J.E. (2012) The use of biomarkers in occupational health research, practice, and policy. Toxicology Letters 213: 91-99. Talaska, G.; Maier, A.; Henn, S.; Booth-Jones, A.; Tsuneoka, Y.; Vermeulen, R.; Schumann, B.L. (2002) Carcinogen biomonitoring in human exposures and laboratory research: validation and application to human occupational exposures. Toxicol. Lett.134: 39-49. Thier, R.; Brüning, T.; Roos, P.H.; Golka, K.; Ko, Y. y Bolt, H.M. (2003) Markers of genetic susceptibility in human environmental hygiene and toxicology: the roles of selected CYP, NAT and GST genes. Int. J. Hyg. Environ. Health206: 149-171. Thybaud, V., Le Fevre, A.-C., and Boitier, E. 2007. Application of toxicogenomics to genetic toxicology risk assessment. Environmental and Molecular Mutagenesis 48:369-379. |
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