Teaching GuideTerm
Faculty of Science
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Mestrado Universitario en Investigación Química e Química Industrial (Plan 2017)
 Subjects
  Chemistry of Biomolecules
   Contents
Topic Sub-topic
Chapter 1. Introduction and historical aspects. Different components of the cell. Organization. Structure and function of main biomolecules
CHAPTER 2. Peptides and proteins. Structural aspects. Synthesis and modification. Design of functional proteins. Metalloproteins: types, methods of study, examples and applications Amino acids and peptides. Proteins and functions. Primary, secondary, tertiary and quaternary structure. Biosynthesis. Chemical synthesis. Modification by chemical methods. Applications.
CHAPTER 3. UNIT 3. Nucleic acids: Structure, DNA synthesis. Sequencing, PCR, DNA Recognition. DNA beyond biology: processing and storage of information; nanomaterials. Structure of the Nucleotides. Structure and function of the different nucleic acids. Supramolecular chemistry of nucleic acids. Biosynthesis. Synthesis and manipulation of nucleic acids by chemical methods. The interaction with small molecules and metal complexes.
CHAPTER 4. Carbohydrates and their derivatives. Structural and synthesis. Glycoconjugates and its role in cellular communication. Glycocode. Glycotherapy Monosaccharides, nomenclature, structure and chemistry. Oligosaccharides and polysaccharides, nomenclature, structure. Structural determination of oligo-and polysaccharides. Biosynthesis, chemical synthesis and biological synthesis of oligosaccharides. Glycosides and glycosidase inhibitors: types, incidence in nature, methods of synthesis and biological applications. Glycolipids. Types of structures. Natural incidence. Biosynthesis. Functions. Glycoproteins. Types of structures. Natural incidence. Biosynthesis. Functions. The glycocode concept. Future prospects and scope thereof. Glycotherapy and Glycoconjugates known functions.
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