Teaching GuideTerm Faculty of Science |
Mestrado Universitario en Investigación Química e Química Industrial (Plan 2017) |
Subjects |
The Chemistry of Natural Products |
Contents |
Identifying Data | 2018/19 | |||||||||||||
Subject | The Chemistry of Natural Products | Code | 610509118 | |||||||||||
Study programme |
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Descriptors | Cycle | Period | Year | Type | Credits | |||||||||
Official Master's Degree | Yearly |
First | Optional | 3 | ||||||||||
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Topic | Sub-topic |
CHAPTER 1. Introduction to the study of natural products | Concepts of natural product and secondary metabolite. Main natural sources. Main applications. Importance of natural products in the pharmaceutical industry. Classification and examples. |
CHAPTER 2. Main metabolic pathways of the secondary metabolism | General scheme of secondary metabolism, main types of natural products that originate and classification based on metabolic pathways. Main mechanisms of biological pathways. Methods of elucidation of a metabolic route. |
CHAPTER 3. Metabolites derived from acetate: poliketides, fatty acids and related compounds | Metabolites derived from acetate: poliketides, fatty acids and related compounds. |
CHAPTER 4. Metabolites derived from mevalonate: terpenes and steroids | Metabolites derived from mevalonate: terpenes and steroids. |
CHAPTER 5. Metabolites derived from shikimic acid | Biosynthetic origen of shikimic acid. Phenylpropanoids. Metabolites of mixed origin: Flavonoids. |
CHAPTER 6. Natural nitrogenous compounds | Aliphatic alkaloids: derivates from lysine and ornithine. Aromatic alkaloids: derivates from phenylalanine/tyrosine and tryptophan. Other estructural frameworks. Biosynthesis of non ribosomal peptides. |
CHAPTER 7. Modernas estrategias de aislamiento e identificación | Traditional methods. Dereplication techniques. Biotechnology strategies based on genetic studies: Genome mining, recombinant biosynthesis and combinatorial biosynthesis. |
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