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Teaching GuideTerm Faculty of Science |
| Mestrado Universitario en Bioloxía Molecular , Celular e Xenética |
 Subjects |
| Genetic Variation Mechanisms |
| Contents |
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| Identifying Data | 2020/21 | |||||||||||||
| Subject | Genetic Variation Mechanisms | Code | 610441005 | |||||||||||
| Study programme |
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| Descriptors | Cycle | Period | Year | Type | Credits | |||||||||
| Official Master's Degree | 1st four-month period |
First | Obligatory | 3 | ||||||||||
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| Topic | Sub-topic |
| Unit 1. Genetic variation: mutation |
Genetic variation and its significance. Origin and consequences of mutation. Chromosome rearrangements. Mutation rates. Reversion and supression. |
| Unit 2. Mobile DNA | Abundance in the genomes. Classification of transposable elements. Proliferation Molecular evolution. Impact on the genomes. Domestication |
| Unit 3.Genetic recombination | Recombination rates. Gene conversion. Sexual dimorphism and recombination rate, crossing-over and gene conversion. Gene conversion bias. |
| Unit 4. Evolution of scientific thought regarding the origin of genetic variability. Woese's contribution. |
Cellular evolution: the path "bumpy" to "who knows where." History of evolutionary thought. State of Microbiology (and Virology) during most of the 20th century. Carl Woese. LUCA. Generation of genetic variability in the beginning of life. |
| Unit 5. Microbial evolution in the genomics era. | The turbulent dynamics of microbial evolution. Damned concepts of classical genetics: genetic elements with a Lamarckian flavor? Evolution of Evolvability? |
| Unit 6. The mysterious world of viruses. | Are viruses alive? Evolution of viruses and viral replicons. Viral Population Dynamics Models |
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