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Facultade de Ciencias
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Mestrado Universitario en Bioloxía Molecular , Celular e Xenética
 Subjects
  Genetic Toxicology
   Sources of information
Basic

BOOKS:

Greim, H.; Snyder, R. (2007) Toxicology and risk assessment: a comprehensive introduction. Chichester: John Wiley & sons.

Klaassen, C.D.; Watkins III, J.B. (2005) Fundamentos de Toxicología de Casarett y Doull. Madrid: MacGraw Hill.

Marquardt, H. ; Schäfer, S.G.; McClellan, R.O.; Welsch, F. (1999) Toxicology. San Diego: Academic Press.

Repetto, M.; Repetto, G. (2009) Toxicología fundamental. Madrid: Díaz de Santos.

Riviere, J.E. (2006) Biological concepts and Techniques in Toxicology. An integrated approach. New York: Taylor & Francis.

Stine, K.E; Brown, T.M. (2006) Principles of toxicology. 2nd edition. Londres: CRC Press Taylor & Francis.

PAPERS:

Albertini, R.J.; Anderson, D.; Douglas, G.R.; Hagmar, L.; Hemminki, K.; Merlo, F.; Natarajan, A.T.; Norppa, H.; Shuker, D.E.G.; Tice, R.; Waters, M.D.; Aitio, A. (2000) IPCS guidelines for the monitoring of genotoxic effects of carcinogens in humans. Mutat. Res.463: 111-172.

Cimino, M. C. 2006. Comparative overview of current international strategies and guidelines for genetic toxicology testing for regulatory purposes. Environmental and Molecular Mutagenesis 47:362-390.

Gallo, V.; Khan, A.; Gonzales, C.; Phillips, D.H.; Schoket, B.; Györffy, E.; Anna, L.; Kovács, K.; Moller, P.; Loft, S.; Kyrtopoulos, S.; Matullo, G.; Vineis, P. (2008) Validation of biomarkers for the study of environmental carcinogens: A review. Biomarkers 13: 505 - 534.

Imyanitov, E.N.; Togo, A.V.; Hanson, K.P. (2004) Searching for cancer-associated gene polymorphisms: promises and obstacles. Cancer Lett.204: 3-14.

Srám, R.J. y Binková, B. (2000) Molecular epidemiology studies on occupational and environmental exposure to mutagens and carcinogens, 1997-1999. Environ. Health Perspect.108: 57-70.

Young, R. 2002. Genetic toxicology: Web resources. Toxicology 173:103-121.

Complementary

BOOKS:

Barile, F.A. (2008) Principles of Toxicology Testing. Florida: CRC Press.

Córdoba, D. (2001) Toxicología. Bogotá: Manual Moderno.

DeCaprio, A. (2006) Toxicologic biomarkers. New York: Taylor and Francis.

Hamadeh, H.K.; Afshari, C.A. (2004) Toxicogenomics. Principles and Applications. New Jersey: Wiley-Liss.

Hodgson, E.; Levi, P.E. (1997) A textbook of modern toxicology. Connecticut: Appleton and Lange.

IPCS (1993) Biomarkers and risk assessment: concepts and principles. International Programme on chemical safety. Environmental Health Criteria 155. World Health Organization. Geneva.

Mendelsohn, M.L.; Mohr, L.C.; Peeters, J.P. (1998) Biomarkers. Medical and workplace applications. Washington D.C.: Joseph Henry Press.

Mendelsohn, M.L.; Peeters, J.P.; Normandy, M.J. (1995) Biomarkers and occupational health: progress and perspectives. Washington D.C.: Joseph Henry Press.

National Research Council of the National Academies (2006) Human biomonitoring for environmental chemicals. Washington D.C.: The National Academies Press.

Niesink, R.J.M. (1996) Toxicology: principles and applications. Boca Raton-Florida: CRC Press.

Repetto, M. (1995) Toxicología avanzada. Madrid: Díaz de Santos.

PAPERS:

Albertini, R.J.; Nicklas, J.A.; O'Neill, J.P. (1996) Future research directions for evaluating human genetic and cancer risk from environmental exposures. Environ. Health Perspect104 (Suppl 3): 503-510.

Au, W.W.; Oh, H.Y.; Grady, J.; Salama, S.A. y Heo, M.Y. (2001) Usefulness of genetic susceptibility and biomarkers for evaluation of environmental health risk. Environ. Mol. Mutagen.37: 215-225.

Autrup, H. (2000) Genetic polymorphisms in human xenobiotica metabolizing enzymes as susceptibility factors in toxic response. Mutat. Res.464: 65-76.

Bonassi, S. (1999) Combining environmental exposure and genetic effect measurements in health outcome assessment. Mutat. Res.428: 177-185.

Butterworth, B.E.; Bogdanffy, M.S. (1999) A comprehensive approach for integration of toxicity and cancer risk assessments. Regul. Toxicol. Pharmacol.29: 23-36.

Garte, S. (2001) Metabolic susceptibility genes as cancer risk factors: time for a reassessment? Cancer Epidemiol. Biomarkers Prev.10: 1233-1237.

Gyorffy, E., Anna, L., Kovacs, K., Rudnai, P., and Schoket, B. (2008) Correlation between biomarkers of human exposure to genotoxins with focus on carcinogen-DNA adducts. Mutagenesis 23:1-18.

Ingelman-Sundberg, M. (2001) Genetic variability in susceptibility and response to toxicants. Toxicol. Lett.120: 259-268.

Lang, M. y Pelkonen, O. (1999) Metabolism of xenobiotic and chemical carcinogenesis. Metabolic polymorphisms and susceptibility to cancer. IARC Scientific Publications No. 148.International Agency for Research on Cancer. Lyon. pp: 13-22.

Norppa, H. (2001) Genetic polymorphisms and chromosome damage. Int. J. Hyg. Environ. Health204: 31-38.

Pavanello, S. (2003) Metabolic and DNA repair variations in susceptibility to genotoxins. Polycyclic Aromatic Compounds23: 49-107.

Pavanello, S. y Clonfero, E. (2000) Biological indicators of genotoxic risk and metabolic polymorphisms. Mutat. Res.463: 285-308.

Seidegard, J. y Ekström, G. (1997) The role of human glutathione transferases and epoxide hydrolases in the metabolism of xenobiotics. Environ. Health Perspect.105: 791-799.

Talaska, G.; Maier, A.; Henn, S.; Booth-Jones, A.; Tsuneoka, Y.; Vermeulen, R.; Schumann, B.L. (2002) Carcinogen biomonitoring in human exposures and laboratory research: validation and application to human occupational exposures. Toxicol. Lett.134: 39-49.

Thier, R.; Brüning, T.; Roos, P.H.; Golka, K.; Ko, Y. y Bolt, H.M. (2003) Markers of genetic susceptibility in human environmental hygiene and toxicology: the roles of selected CYP, NAT and GST genes. Int. J. Hyg. Environ. Health206: 149-171.

Thybaud, V., Le Fevre, A.-C., and Boitier, E. 2007. Application of toxicogenomics to genetic toxicology risk assessment. Environmental and Molecular Mutagenesis 48:369-379.

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