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Teaching GuideTerm Faculty of Science |
| Mestrado Universitario en Investigación Química e Química Industrial (Plan 2017) |
 Subjects |
| The Chemistry of Natural Products |
| Contents |
| Identifying Data | 2018/19 | |||||||||||||
| Subject | The Chemistry of Natural Products | Code | 610509118 | |||||||||||
| Study programme |
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| Descriptors | Cycle | Period | Year | Type | Credits | |||||||||
| Official Master's Degree | Yearly |
First | Optional | 3 | ||||||||||
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| Topic | Sub-topic |
| CHAPTER 1. Introduction to the study of natural products | Concepts of natural product and secondary metabolite. Main natural sources. Main applications. Importance of natural products in the pharmaceutical industry. Classification and examples. |
| CHAPTER 2. Main metabolic pathways of the secondary metabolism | General scheme of secondary metabolism, main types of natural products that originate and classification based on metabolic pathways. Main mechanisms of biological pathways. Methods of elucidation of a metabolic route. |
| CHAPTER 3. Metabolites derived from acetate: poliketides, fatty acids and related compounds | Metabolites derived from acetate: poliketides, fatty acids and related compounds. |
| CHAPTER 4. Metabolites derived from mevalonate: terpenes and steroids | Metabolites derived from mevalonate: terpenes and steroids. |
| CHAPTER 5. Metabolites derived from shikimic acid | Biosynthetic origen of shikimic acid. Phenylpropanoids. Metabolites of mixed origin: Flavonoids. |
| CHAPTER 6. Natural nitrogenous compounds | Aliphatic alkaloids: derivates from lysine and ornithine. Aromatic alkaloids: derivates from phenylalanine/tyrosine and tryptophan. Other estructural frameworks. Biosynthesis of non ribosomal peptides. |
| CHAPTER 7. Modernas estrategias de aislamiento e identificación | Traditional methods. Dereplication techniques. Biotechnology strategies based on genetic studies: Genome mining, recombinant biosynthesis and combinatorial biosynthesis. |
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