Teaching GuideTerm
Faculty of Health Sciences
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Mestrado Universitario en Asistencia e Investigación Sanitaria (plan 2012)
 Subjects
  Clinical Research I
   Contents
Topic Sub-topic
Normality test 1. Graphic methods
2. Analytical methods
Two-Sample Inference 1. Two-Sample Inference for related variables.
2. Two-Sample Inference for independent variables
Introduction to the Analysis of Variance 1. ANOVA models
2. Nonparametric alternatives to ANOVA
Sample size determination 1. Determination of sample size for estimating parameters.
2. Determination of sample size for testing hypotheses.
3. Sample size calculations for case-control studies.
4. Sample size calculations in studies monitoring.
5. Determination of sample size for estimating correlation coefficient.
Validation of diagnostic test 1. Validity and reliability of diagnostic tests: sensitivity, specificity, predictive values, likelihood ratios
2. The clinical application of Bayes' theorem
3. Receiver-operating characteristics (ROC) curves and área under the curve
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