| Study programme competencies |
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Code
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Study programme competences
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| A1 |
Define concepts, principles, theories and specialized facts of different areas of chemistry. |
| A2 |
Suggest alternatives for solving complex chemical problems related to the different areas of chemistry. |
| A4 |
Innovate in the methods of synthesis and chemical analysis related to the different areas of chemistry |
| B1 |
Possess knowledge and understanding to provide a basis or opportunity for originality in developing and / or applying ideas, often within a research context |
| B4 |
Students should be able to communicate their conclusions, and the knowledge and the reasons that support them to specialists and non-specialists in a clear and unambiguous manner |
| B5 |
Students must possess learning skills to allow them to continue studying in a way that will have to be largely self-directed or autonomous. |
| B7 |
Identify information from scientific literature by using appropriate channels and integrate such information to raise and contextualize a research topic |
| B10 |
Use of scientific terminology in English to explain the experimental results in the context of the chemical profession |
| B11 |
Apply correctly the new technologies to gather and organize the information to solve problems in the professional activity. |
| Learning aims |
| Learning outcomes |
Study programme competences |
| Know in full the main mechanisms of organic reactions. |
AC1
AC2
AC4
|
BC1
BC4
BC5
BC7
BC10
BC11
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| Know the main methods used in the determination of mechanism in organic chemistry. |
AC1
AC2
AC4
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BC1
BC4
BC5
BC7
BC10
BC11
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| Study in depth the synthetic methodology used in the preparation of organic compounds. |
AC1
AC2
AC4
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BC1
BC4
BC5
BC7
BC10
BC11
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| Contents |
| Topic |
Sub-topic |
| Topic 1. Mechanisms of organic reactions |
Introduction: reaction mechanisms, transition state, activation energy. Thermodynamic and kinetic control. Effect of solvent. Hammond postulate, Curtin-Hammett principle. Determination of reaction mechanisms. Effect of substituents: Hammett equation. Isotope effects. Acid and base catalysis. Characterization of intermediates. |
| Topic 2. Pericyclic reactions. |
Frontier orbital theory. Woodward and Hoffmann rules. Cycloadditions: Diels-Alder reaction, [2 + 2], [3 + 2]. Sigmatropic rearrangements: Claisen, Cope, [2,3], [1, n], ene, cheletropic. Electrocyclic reactions. |
| Topic 3. Radicals and carbenes. |
Structure. Preparation of radicals. Radical reactions: coupling, addition, fragmentation and transpositions. Formation of C-C inter- and intramolecular. Radical formation induced by metals. Carbenes. Diazomethane. Carbenes types. Reactions of carbenes: insertion into C-H bonds, rearrangements, metathesis. |
| Topic 4. Photochemical reactions. |
General principles. Photochemistry and orbital structure. Photochemistry of carbonyl compounds, alkenes and dienes, and aromatics. |
| Topic 5. Synthetic methods and applications. |
Introduction. Protecting groups. Synthetic equivalents. Retrosynthetic analysis: disconnections, chemoselectivity, functional group interconversion. Asymmetric synthesis, chiral pool, auxiliaries and chiral reagents, asymmetric catalysis. Examples. |
| Planning |
| Methodologies / tests |
Competencies |
Ordinary class hours |
Student’s personal work hours |
Total hours |
| Guest lecture / keynote speech |
A1 A2 A4 B7 B10 B11 |
16 |
16 |
32 |
| Problem solving |
A1 A2 A4 B1 B7 B10 B11 |
6 |
18 |
24 |
| Mixed objective/subjective test |
A1 A2 A4 B1 B4 B5 B7 B10 B11 |
2 |
0 |
2 |
| |
| Personalized attention |
|
2 |
0 |
2 |
| |
| (*)The information in the planning table is for guidance only and does not take into account the heterogeneity of the students. |
| Methodologies |
|
Methodologies |
Description |
| Guest lecture / keynote speech |
Lección impartida polo profesor que pode ter formatos diferentes (teoría, problemas e/ou exemplos xerais, directrices xerais da materia...). O profesor pode contar con apoio de medios audiovisuais e informáticos pero, en xeral, os estudantes non necesitan manexalos en clase. Habitualmente estas clases seguirán os contidos dun Manual de referencia proposto na Guía Docente da materia. A asistencia a estas clases non é obrigatoria, pero resulta moi recomendable. |
| Problem solving |
Clase teórico/práctica na que se propoñen e resolven aplicacións da teoría, problemas, exercicios. O alumno participa activamente nestas clases de distintas formas: entrega de exercicios ao profesor (algúns dos propostos en boletíns de problemas que o profesor entrega aos alumnos coa suficiente antelación); resolución de exercicios na aula, etc. O profesor pode contar con apoio de medios audiovisuais e informáticos pero, en xeral, os estudantes non os manexarán en clase. Inclúense as probas de avaliación se as houber. A asistencia a estas clases é obrigatoria. |
| Mixed objective/subjective test |
O exame final versará sobre a totalidade dos contidos da materia. |
| Personalized attention |
|
Methodologies
|
| Problem solving |
|
| Description |
| Scheduled by the teacher and coordinated by the Center. In general, each student will account for two hours per semester and subject. Monitoring activities as directed exercises, clarification of doubts about the theory or practice, problems, exercises, readings or other proposed tasks are proposed; and the presentation, presentation, discussion or comment made work individually or in small groups. In many cases the teacher will require students exercises delivery prior to the celebration of mentoring. These deliveries will come included in the calendar of activities to be undertaken by students throughout the course in the Teaching Guide of the corresponding subject. Attendance at these classes is mandatory. |
|
| Assessment |
|
Methodologies
|
Competencies |
Description
|
Qualification
|
| Mixed objective/subjective test |
A1 A2 A4 B1 B4 B5 B7 B10 B11 |
O exame final versará sobre a totalidade dos contidos da materia. |
60 |
| Problem solving |
A1 A2 A4 B1 B7 B10 B11 |
A avaliación continua terá un peso do 40% na cualificación da materia e constará de dous compoñentes: clases de resolución de problemas e seminarios. A resolución de problemas e casos prácticos computará un 20%. Terase en conta así mesmo a asistencia e participación do alumno (10%). |
30 |
| |
|
Assessment comments |
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| Sources of information |
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Basic
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Carey, F. A.; Sundberg, R. J. (2007). Advanced Organic Chemistry; 5th Ed.. Springer
Smith, M. B.; March, J. (2013). March's Advanced Organic Chemistry; 7th Ed.. Wiley
Clayden, J.; Greeves, N.; Warren, S. (2012). Organic Chemistry, 2nd Ed.. Oxford University press
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Complementary
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| Recommendations |
| Subjects that it is recommended to have taken before |
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| Subjects that are recommended to be taken simultaneously |
| Profundización en Química Analítica/610509001 | | Profundización en Química Física/610509002 | | Profundización en Química Inorgánica/610509003 |
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| Subjects that continue the syllabus |
| Análise Estrutural Avanzado/610509005 | | Mecanismos de reacción e catálise/610509009 | | Compostos organometálicos en síntese e catálise /610509011 | | Síntese estereoselectiva/610509012 | | Produtos e técnicas sintéticas/610509013 |
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