Study programme competencies |
Code
|
Study programme competences / results
|
A1 |
Define concepts, principles, theories and specialized facts of different areas of chemistry. |
A2 |
Suggest alternatives for solving complex chemical problems related to the different areas of chemistry. |
A3 |
Innovate in the methods of synthesis and chemical analysis related to the different areas of chemistry |
A4 |
Apply materials and biomolecules in innovative fields of industry and chemical engineering. |
A9 |
Promote innovation and entrepreneurship in the chemical industry and in research. |
B1 |
Possess knowledge and understanding to provide a basis or opportunity for originality in developing and / or applying ideas, often within a research context |
B2 |
Students should apply their knowledge and ability to solve problems in new or unfamiliar environments within broader (or multidisciplinary) contexts related to their field of study. |
B4 |
Students should be able to communicate their conclusions, and the knowledge and the reasons that support them to specialists and non-specialists in a clear and unambiguous manner |
B5 |
Students must possess learning skills to allow them to continue studying in a way that will have to be largely self-directed or autonomous. |
B7 |
Identify information from scientific literature by using appropriate channels and integrate such information to raise and contextualize a research topic |
B10 |
Use of scientific terminology in English to explain the experimental results in the context of the chemical profession |
B11 |
Apply correctly the new technologies to gather and organize the information to solve problems in the professional activity. |
C1 |
CT1 - Elaborar, escribir e defender publicamente informes de carácter científico e técnico |
C3 |
CT3 - Traballar con autonomía e eficiencia na práctica diaria da investigación ou da actividade profesional. |
C4 |
CT4 - Apreciar o valor da calidade e mellora continua, actuando con rigor, responsabilidade e ética profesional. |
Learning aims |
Learning outcomes |
Study programme competences / results |
Knowing the fundamental role that primary metabolites (carbohydrates, proteins , peptides and nucleic acids ) play in living organisms . |
AC2 AC3 AC4
|
BC5 BC10 BC11
|
|
Gain knowledge of instrumental techniques for the isolation and structural determination of these natural substances. |
AC1 AC9
|
BC1 BC2 BC4 BC7
|
CC4
|
Knowing the value of its synthesis in the development of biologically active compounds. |
AC2 AC4
|
BC2 BC5 BC7
|
CC1 CC3
|
Contents |
Topic |
Sub-topic |
UNIT 1. Introduction and historical aspects |
Introduction and historical aspects |
UNIT 2. Peptides and proteins |
Structural aspects. Synthesis and modification. Design of functional proteins. Metalloproteins: types, methods of study, examples and applications |
UNIT 3. Nucleic acids |
Structure, DNA synthesis. Sequencing, PCR, DNA Recognition. DNA beyond biology: processing and storage of information; nanomaterials. |
UNIT 4. Carbohydrates |
Structural aspects. Synthesis and modification. Glycoconjugates and its role in cellular communication. Glycocode. Glycotherapy |
Planning |
Methodologies / tests |
Competencies / Results |
Teaching hours (in-person & virtual) |
Student’s personal work hours |
Total hours |
Guest lecture / keynote speech |
B2 B5 C3 C4 |
12 |
24 |
36 |
Seminar |
A1 A2 A4 B1 B4 B7 B10 B11 C1 |
7 |
18 |
25 |
Mixed objective/subjective test |
A1 A4 A3 A9 B1 B2 B5 |
2 |
10 |
12 |
|
Personalized attention |
|
2 |
0 |
2 |
|
(*)The information in the planning table is for guidance only and does not take into account the heterogeneity of the students. |
Methodologies |
Methodologies |
Description |
Guest lecture / keynote speech |
It is proposed to carry out 12 sessions of master classes in a single group where the theoretical contents of the subject will be developed together with the corresponding illustrative examples. It will consist mainly of Power Point presentations. The students will have, with sufficient time in advance, copies of the corresponding presentations through the virtual classroom, so that the student can previously prepare the subject that is going to be taught in addition to facilitate the follow-up of the explanations. The interactive participation of the student will be encouraged at all times. Attendance to these classes is not compulsory, but it is highly recommended. |
Seminar |
Resolution of practical exercises (problems, multiple choice questions, interpretation and processing of information, evaluation of scientific publications, etc.).
Oral presentation of papers, reports, etc., including discussions with teachers and students. |
Mixed objective/subjective test |
The final exam will cover all the contents of the course |
Personalized attention |
Methodologies
|
Seminar |
Mixed objective/subjective test |
|
Description |
Tutorials are scheduled by the professor and coordinated by the Center. In general, each student will have 2 hours per term and subject. Activities such as supervision of directed work, clarification of doubts about theory or practices, problems, exercises, readings or other proposed tasks are proposed; as well as the presentation, exposition, debate or commentary of individual work or work done in small groups. In many cases the professor will require the students to hand in exercises prior to the tutorial. These deliveries will be included in the calendar of activities to be carried out by the students throughout the course in the Teaching Guide of the corresponding subject. Attendance to these classes is compulsory. |
|
Assessment |
Methodologies
|
Competencies / Results |
Description
|
Qualification
|
Seminar |
A1 A2 A4 B1 B4 B7 B10 B11 C1 |
Within the continuous evaluation (N1), a series of evaluable activities will be carried out in the seminars: resolution of practical cases, completion of assignments and written reports. Likewise, the student will present orally, throughout the course, one or more of the results obtained in the activities proposed in the seminars. |
45 |
Mixed objective/subjective test |
A1 A4 A3 A9 B1 B2 B5 |
The final exam (N2) will cover all subjects. |
55 |
|
Assessment comments |
The qualification of this subject will be done through continuous evaluation and the completion of a final exam. In order to access the exam it is necessary to participate in 100% of the teaching activities of compulsory attendance (classes, seminars and tutorials). Continuous assessment (N1) will weigh 45% of the course grade and consists of two components: interactive classes in small groups (seminars) and interactive classes in very small groups (tutorials). Seminars and tutorials will include problem solving and case studies (40%), oral questions and problems during the course (5%). The final exam (N2) will cover the totality of the content of the subject and will have a value of 55%. The student's score will be obtained as a result of the application of the following formula: final grade = 0.45 x N1 + 0.55 x N2 N1 corresponds to the continuous evaluation (scale of 0-10) and N2 to the final exam (scale of 0-10). A minimum grade of 4 in the final exam will be required to pass the course.
|
Sources of information |
Basic
|
Davies, B.G.; Fairbanks. A.J. (2004). Carbohydrate Chemistry. Oxford Science publications
Peng G. Wang, C. R. Betozzi. Marcel Dekker (2001). Glycochemistry, Principles, Synthesis and Applications..
Driguez, H; Thiem (1997). Glycoscience, Synthesis of Substrate Analogs and Mimetics.. J. Springer-Verlag
Vranken, D-V; Weiss, G.A. (2012). Introduction to Bioorganic Chemistry and Chemical Biology. Garland Science
Taylor, M.E.; Drickamer, K. (2011). Introduction to Glycobiology. Oxford University press
Brändén, C-I; Tooze, J. (1999). Introduction to Protein Structure. Garland Science
Alberts et all (2002). Molecular Biology of the Cell. Garland Science
Blackburn, M.: Gait, M.J.; Loakes, D.; Williams, D.M. (2006). Nucleic Acids in Chemistry and Biology. Rayal Society of Chemistry
Dr. Norbert Sewald, Prof. em. Dr. Hans-Dieter Jakubke, (2009). Peptides: Chemistry and Biology. John-Wiley
Gutte, B. (1995). Peptides: Synthesis, Structures and Application. Academic Press
D. Serge (1997). The Molecular and Supramolecular Chemistry of Carbohydrates. A chemical introduction to glicoscience.. Oxford Science publications
Chris R. Calladine, Horace R. Drew, Ben F. Luisi and Andrew A. Travers (2004). Understanding DNA, The Molecule & how It Works. Elsevier |
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Complementary
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Recommendations |
Subjects that it is recommended to have taken before |
Advanced Structural Determination/610509103 | Structure and Reactivity of Organic Compounds /610509114 |
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Subjects that are recommended to be taken simultaneously |
Chemistry of Natural Products/610509118 | Molecular Biology/610509117 | Medicinal Chemistry/610509116 |
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Subjects that continue the syllabus |
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Other comments |
It is very important to attend the lectures. It is essential to carry out a continuous study of the subject. Once the class is over, it is useful to summarize the most important points. The resolution of exercises is key to the learning of this subject. It may be helpful to start with the problems solved in the support and reference manuals, to continue with the problems proposed at the end of each chapter. |
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