Identifying Data 2023/24
Subject (*) Advanced Cellular Biology Code 610441003s
Study programme
Máster Universitario en Bioloxía Molecular, Celular e Xenética (semipresencial)
Descriptors Cycle Period Year Type Credits
Official Master's Degree 1st four-month period
First Obligatory 3
Language
Spanish
Galician
Teaching method Hybrid
Prerequisites
Department Bioloxía
Coordinador
Yañez Sanchez, Julian
E-mail
julian.yanez@udc.es
Lecturers
Díaz Prado, María Luz
Yañez Sanchez, Julian
E-mail
luz.diaz@udc.es
julian.yanez@udc.es
Web http://https://campusvirtual.udc.gal
General description Actualmente a bioloxía celular como disciplina medróu e maduróu significativamente de xeito que os seus límites conceptuais son moitas veces difusos e difíciles de definir. Así, Citoloxia, Bioquímica, Bioloxía Molecular, Xenética e Fisioloxía celular superpóñense en moitos aspectos. En realidade, calquer avance substancial destas áreas implica a utilización de metodoloxías tipificado nunha ou máis dunha área.
Este curso céntrase na estrutura e función dos compoñentes celulares cunha visión holística das interaccións entre eses compoñentes para asegurar o bo funcionamento da célula. Sabemos que non é posible cubrir nun único curso todos os contínuos avances en profundidade, polo que trataranse ao longo do curso de aqueles aspectos de relevancia particular para dar unha idea da complexidade subxacente dos procesos celulares.
Como éste é un curso avanzado, presúmese que os alumnos teñan coñecementos básicos de Bioloxia celular, xenética, fisioloxía, bioquímica e bioloxía molecular.

Study programme competencies
Code Study programme competences
A1 Skills of working in a sure way in the laboratories knowing operation handbooks and actions to avoid incidents of risk.
A2 Skills of using usual techniques and instruments in the cellular, biological and molecular research: that are able to use techniques and instruments as well as understanding potentials of their uses and applications.
A6 Skills of understanding the functioning of cells through the structural organization, biochemistry, gene expression and genetic variability.
A7 Skills of knowing and analyzing specific cellular systems as stem cells, nerve cells, cells of the immune system, or other cells related to several pathologies.
A13 Skills to become a professional in health, pharmacy, veterinary, animal production, biotechnology or food sectors.
B5 Ability to draft, represent, analyze, interpret and present technical documentation and relevant data in the field of the branch of knowledge of the master's degree in the native language and at least in another International diffusion language.
B9 Skills of preparation, show and defense of a work.
C1 Ability to express oneself correctly, both orally and in writing, in the official languages of the autonomous community

Learning aims
Learning outcomes Study programme competences
Skills of understanding the functioning of cells through the structural organization. AR6
AR7
BR5
BR9
CC1
Skills to apply immunohistochemical techniques to the study of cell components AR1
AR2
AR13

Contents
Topic Sub-topic
Introduction to cell Cell Domains and the origin of multicellularity.
Integrative view of the eukaryote cell
Structure and dynamics of the cell nucleus Structure of nuclear envelope
Nucleocytoplasmic traffic.
Cell nucleus organization: chromatinic territories and nuclear subdomains.
Biogenesis, trafficking and functions of the cell endomembrane system Structure and membrane domains.
Membrane compartments and vesicular trafficking.
Traffic RE-Golgi complex.
Endosomes and endocytosis.
Traffic between the Golgi complex and endosomes.
The secretory pathway of the Golgi complex: conventional and unconventional exocytosis.
Lipid trafficking between compartments.
Post-translational targeting of cytosolic proteins to organelles.
Degradation of cellular components.
Cytoskeleton and cell dynamic. Microtubules and associated proteins.
Microtubule complex structures.
Microfilaments and associated proteins.
Cell motility and contractile systems.
Cytoskeleton and cytokinesis.
Intermediate filaments. Septins.
Interactions cell to cell and cell to extracellular matrix Cell adhesion and junctions
Extracellular matrix molecules
Pathological alterations of the extracellular matrix.

Planning
Methodologies / tests Competencies Ordinary class hours Student’s personal work hours Total hours
Guest lecture / keynote speech A6 A7 8 16 24
Document analysis A6 A13 B5 B9 C1 4 12 16
Laboratory practice A1 A2 10 20 30
Mixed objective/subjective test A6 2.5 0 2.5
 
Personalized attention 2.5 0 2.5
 
(*)The information in the planning table is for guidance only and does not take into account the heterogeneity of the students.

Methodologies
Methodologies Description
Guest lecture / keynote speech This activivity includes the personal work (not face-to-face) on various study materials available in the web page of the subject for the students and that cover the different contents. These materials include multimedia files, specific readings, educational videos, self-assessment tests, ...
Document analysis Consist of reading of recent articles in Cell Biology on a topic previously designated that complements or completes the contents of the subject. As a result of this work, a written review should be presented that will be also available to classmates. In addition, also on the subject page, a discussion forum will be opened for a limited time to make contributions and resolve doubts about the published topics.
Laboratory practice It will consist of the application of immunohistochemical methods for the analysis and study of certain cellular structures or components.
Mixed objective/subjective test It will consist of an exam with choice questions and/or short questions on the contents of the topic treated in lectures and seminars.

Personalized attention
Methodologies
Guest lecture / keynote speech
Description
The lecturer will have at least by appointment, an interview via MS Teams at the beginning of the course to meet personally with each student and resolve any questions about the organization of the course. Each student will have the opportunity to consult specific questions of the subject at any time during the weeks of the activities via E-mail. Alternatively, when the nature and extent of the problem would be required, students have up to 4 appointments by videoconference through MS Teams throughout the semester, including the dates prior to the exam of both opportunities.

Assessment
Methodologies Competencies Description Qualification
Document analysis A6 A13 B5 B9 C1 It will be assesed the degree of understanding of the subject of the bibliographic review and its written presentation, which will be published in the web page of the subject. In addition, participation in a specific forum will be also valued, answering the questions posted by the teacher and other colleagues as well as the relevant contributions to the topics discussed 30
Mixed objective/subjective test A6 It will consist of the resolution of questions (short answer and multiple choice, order, complete or associate) and / or some cases about the contents of the topics covered in the keynote sessions or discussed in the forum.
The exam will be carried out electronically through the Faculty's virtual platform and with simultaneous connection through MS Teams.
70
 
Assessment comments

Exceptionally, when the student by justified reasons (part-time students or specific circumstances of learning) or unexpected circumnstances were not be able to take all the continuous assessment tests the teacher can adapt the appropriate measures or activities trying not to harm student scores for those reasons.

In the case of the second opportunity of the current year (July) there will be an exam with 100% consideration for the final grade.

Students will take their exam online on the official date (via moodle and MS Teams).

The fraudulent performance of tests or evaluation
activities, once verified, will directly imply the grade of failing "0"
in the corresponding opportunity.
Honors will be preferentially granted among the students of the first call.

General criteria of UDC will be applied in the commitment respect enviromental values and gender perspective.


Sources of information
Basic Pollard, T.D; Earnshaw WC (2002, 2008). Cell Biology. Saunders
Alberts, B.; Johnson A.; Lewis, J.; Raff, M.; Roberts, R. & Walter, P (2008-2015). Molecular Biology of the cell. Garland

Complementary Lodish, H.; Berk, A.; Zypursky, S.; Matsudaira, P.; Baltimore, D.; Darnell, J. (2013). Molecular cell biology. Macmillan

Enlaces de interés/ Links of interest:

IBIOSEMINARS

Virtual cell animation collection

Saylor Academy: Cell biology lectures


Recommendations
Subjects that it is recommended to have taken before

Subjects that are recommended to be taken simultaneously

Subjects that continue the syllabus

Other comments


(*)The teaching guide is the document in which the URV publishes the information about all its courses. It is a public document and cannot be modified. Only in exceptional cases can it be revised by the competent agent or duly revised so that it is in line with current legislation.