Study programme competencies |
Code
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Study programme competences
|
A1 |
Recoñecer distintos niveis de organización nos sistemas vivos. |
A2 |
Identificar organismos. |
A11 |
Identificar e analizar material de orixe biolóxica e as súas anomalías. |
A16 |
Realizar cultivos celulares e de tecidos. |
A26 |
Deseñar experimentos, obter información e interpretar os resultados. |
A29 |
Impartir coñecementos de Bioloxía. |
A30 |
Manexar adecuadamente instrumentación científica. |
A31 |
Desenvolverse con seguridade nun laboratorio. |
B1 |
Aprender a aprender. |
B2 |
Resolver problemas de forma efectiva. |
B3 |
Aplicar un pensamento crítico, lóxico e creativo. |
B5 |
Traballar en colaboración. |
B6 |
Organizar e planificar o traballo. |
B8 |
Sintetizar a información. |
B9 |
Formarse unha opinión propia. |
B10 |
Exercer a crítica científica. |
B11 |
Debater en público. |
B13 |
Comportarse con ética e responsabilidade social como cidadán e como profesional. |
Learning aims |
Learning outcomes |
Study programme competences |
Deepen your knowledge of the organization of hereditary material with an evolutionary approach through the study of chromosomes and their variations. |
A1 A11 A16 A26 A30 A31
|
B1 B2 B3 B5 B6 B8 B9 B10 B11
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|
Deepen your knowledge of the organization of hereditary material with an evolutionary approach through the study of chromosomes and their variations. |
A1 A2 A11 A16 A30 A31
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B1 B2 B3 B5 B6 B10 B11
|
|
To understand the fundamentals involve when learning about chromosome and familiar with the basic methodology employed for the study of chromosomes.
Tools for cytogenetics. |
A1 A2 A11 A16 A30 A31
|
B1 B2 B3 B5 B6 B11 B13
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To understand the fundamentals involve when learning about chromosome and familiar with the basic methodology employed for the study of chromosomes.
Tools for cytogenetics. |
A1 A2 A11 A16 A30 A31
|
B1 B2 B3 B5 B6 B11 B13
|
|
Search and use of different literature and databases that allow carrying out the scientific approach to a topic related to chromosomes sources, organization, function and evolution.
Management information sources of interest in cytogenetics. |
A29
|
B1 B2 B3 B5 B6 B11 B13
|
|
Contents |
Topic |
Sub-topic |
Topic 1. Organization and structure of the eukaryotic chromosome |
O DNA no cromosoma: DNA de copia única, DNA moderadamente repetitivo, DNA altamente repetitivo, secuencias esenciales: CEN, TEL e ARS.
A proteínas cromosómicas: histonas e non histonas. Tipos, modificacións e funcións.
|
Topic 2. From chromatin to metaphase chromosome |
Organización da cromatina en interfase: o nucleosoma, a fibra fundamental, os bucles e as SARs.
Os territorios cromosómicos.
Organización do cromosoma en metafase: condensinas e andamio de proteínas non histónicas.
Tipos de cromatina.
O cariotipo.
|
Topic 3. The longitudinal differentiation of chromosomes |
O bandeo de cromosomas. Tipos de bandas.
Significado estructural e funcional das bandas.
As isocoras.
|
Topic 4. Chromosome replication and trancription |
Ciclo celular e replicación.
Replicación da cromatina e acoplamento das histonas.
A transcripción da fibra de cromatina: eucromatina e heterocromatina.
Os cromosomas plumosos e os cromosomas politénicos.
|
Topic 5. Mitosis and changes in cell division |
Características principais da mitosis
Intercambio entre cromátidas
Control da separación de cromátidas irmáns |
Topic 6. Meiosis and changes of chromosome behaviour |
Caracterísiticas principais da meiosis
Complexos sinaptonémicos
Recombinación e nódulos de recombinación
Os quiasmas: frecuencia e distribución
Segregación cromosómica e cromatídica
|
Topic 7. Chromosome sex determination |
Sistemas cromosómicos de determinación do sexo
A haplodiploidía.
Heterocromatinización e sexo.
Orixen dos cromosomas sexuais |
Topic 8. Structural chromosome changes |
Delecions: clases e orixen. Consecuencias xenéticas
Duplicacions: clases, oricen, consecuencias e relevancia no proceso evolutivo.
Inversions: clases, orixen, comportamento meiótico, consecuencias e relevancia no proceso evolutivo.
Translocacions: clases, orixen, comportamento meiótico, consecuencias e relevancia no proceso evolutivo.
|
Topic 9. Poliploydy, haplodiploydy and anepuloydy |
Orixen, identificación, tipos, comportamento meiótico, consecuencias, e importancia evolutiva.
Os cromosomas B
Amplificación xénica
|
Topic 10. Methodologies and development of technologies |
Hibridación in situ fluorescente.
Cariotipos espectrales.
Citometría de fluxo.
Microdisección e microclonación de cromosomas ou bandas cromosómicas.
|
Laboratory practices |
1. Cultivos celulares e obtención de cromosomas metafásicos
2. Inducción de bandas cromosómicas e estudo da actividade NOR
3. Elaboración de cariotipos
|
Planning |
Methodologies / tests |
Competencies |
Ordinary class hours |
Student’s personal work hours |
Total hours |
Guest lecture / keynote speech |
A1 A2 A11 A16 A26 A29 A30 A31 B1 B2 B3 B5 B6 B8 B9 B10 B11 B13 |
21 |
52.5 |
73.5 |
Laboratory practice |
A1 A2 A11 A16 A31 B1 B2 B3 B5 B6 B13 |
14 |
28 |
42 |
Mixed objective/subjective test |
B1 B2 B8 B9 B13 |
1.5 |
0 |
1.5 |
Workbook |
A26 B1 B2 B5 B6 B8 B13 |
0 |
6 |
6 |
Practical test: |
B1 B2 B13 |
1 |
0 |
1 |
Oral presentation |
A29 B1 B3 B8 B9 B11 B13 |
5 |
17 |
22 |
|
Personalized attention |
|
4 |
0 |
4 |
|
(*)The information in the planning table is for guidance only and does not take into account the heterogeneity of the students. |
Methodologies |
Methodologies |
Description |
Guest lecture / keynote speech |
In the lectures, the lecturers will explain the fundamental contents of each subject of the programme and will indicate the associated activities. These will include bibliographic consultation, the resolution of question and problem papers, or the elaboration of a work to be carried out by the student in a group or individually. |
Laboratory practice |
The practical classes will comprise an explanation by the lecturers of the conceptual basis, the objectives to be achieved, the development of tasks by the student, following a previously provided script. The aim is for the student to have maximum autonomy, providing him with the means and guidance. |
Mixed objective/subjective test |
The mixed test will consist of short questions or test-type questions and resolution of exercises and problems. |
Workbook |
The student will read one or two scientific articles to deepen the contents of the syllabus, and will present them orally.
|
Practical test: |
The knowledge acquired during the laboratory practicals will be assessed. |
Oral presentation |
It will consist of the presentation of one or two scientific articles, accompanied by a power point presentation, which will later be hosted on the Moodle platform of the subject for consultation by the rest of the students in order to complete the contents of the subject. The presentation will last 10-12 minutes. This activity will be carried out in pairs and both members of the group will share the presentation of the work. |
Personalized attention |
Methodologies
|
Practical test: |
Workbook |
Laboratory practice |
Oral presentation |
Guest lecture / keynote speech |
|
Description |
Throughout the course, the teacher will be available during the hours of interactive lectures, group tutorials / small group and individual tutoring for answering questions, guiding the development of seminars / group work and all matters related to the organization of matter.
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Assessment |
Methodologies
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Competencies |
Description
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Qualification
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Practical test: |
B1 B2 B13 |
Se valorará os conocimientos adquiridos durante as prácticas de laboratorio. |
15 |
Laboratory practice |
A1 A2 A11 A16 A31 B1 B2 B3 B5 B6 B13 |
Take into account the interest to learn techniques on chromosomes, skill in the laboratory experiments ability to solve chromosomes and the attitude and ability to function in the laboratory. |
20 |
Mixed objective/subjective test |
B1 B2 B8 B9 B13 |
Avaliarase mediante unha proba obxectiva os coñecementos adquiridos durante as clases expositivas e as clases en grupo interactivo. |
40 |
Oral presentation |
A29 B1 B3 B8 B9 B11 B13 |
Avaliarase a exposición oral e a presentación en power point do traballo realizado polo alumno tendo en conta a capacidade para extraer o más relevante dos artículos científicos empregados, a capacidade de traballar en grupo, a expresión oral e corporal, e a capacidade de síntese. |
25 |
|
Assessment comments |
Laboratory practices are mandatory. It will be considered NOT PRESENTED when the student has not participated in more than 20% of the scheduled assessable activities. This criterion applies to the January call. In the July call, to obtain the grade NOT PRESENTED, it will be enough to not appear for the objective tests (theory and practical exams). For the evaluation of the July call, the student, in addition to the theory and practical exams, must present the bulletins of solved problems and the power point presentation of the oral presentation. In the event that these last two activities were already evaluated in the January call, the grade obtained will remain for July. For students with part-time dedication and exemption from attendance, the teacher will adopt the measures that he deems appropriate to avoid damaging her grade (flexibility in the delivery dates of the assessable activities). Instead of the oral presentation, these students will make a 2-3 page summary that must be delivered in pdf to the teacher for evaluation. The fraudulent performance of tests or assessment activities will directly imply the application of current regulations in the UDC.
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Recommendations |
Subjects that it is recommended to have taken before |
Biology: Basic Levels of Organisation of Life I (Cells)/610G02007 | Genetics/610G02019 | Molecular Genetics/610G02020 |
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Subjects that are recommended to be taken simultaneously |
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Subjects that continue the syllabus |
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Other comments |
Attendance at lectures makes it possible to deal with any doubts or
questions that may arise in the course of the explanations, facilitating
the understanding of the subjects. Study should include regular reading
of at least the recommended bibliography. Group study and work favours
understanding and develops a critical spirit. The doubts and
difficulties that arise in any aspect of the subject will be resolved as
soon as possible, raising them in the classroom or attending individual
tutorials. Given that part of the recommended bibliography for this
subject is in English, it is recommended to have a good command of this
language, at least at the level of comprehension of written texts. Gender Perspective In
this subject, the gender perspective will be taken into account, sexist
attitudes will not be tolerated and the values of respect and equality
will be promoted.
Program Green Campus
Empower of Sciences To help to achieve some sustainable immediate surroundings
and fulfil with the point 6 of the Environmental Statement of the faculty of
Sciences (2020), the documentary works that realise  in this matter: to. They will request 
mostly in virtual format and computer support b. To realise  in
paper: -they will not employ 
plastic -will realise 
impressions to double expensive -will employ  paper
recycled -will avoid  the
realisation of drafts To Environmental Statement is available in: https://ciencias.udc.es/images/Facultade/Green_Campus/Regulamento_Comit%C3%A9_Green_Campus_FCiencias.pdf |
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