- To pass the subject it will be necessary to achieve, added the qualifications of all the continuous evaluation activities (Seminars and Laboratory Practices), a minimum of 5 points (out of 10) and obtain a minimum of 5 points (out of 10) in the qualification of the mixed test. In the event that the students do not achieve the minimum score in any of them, if the sum of the set of all evaluable activities is greater than or equal to 5 points, the subject will appear as failed (4.5 out of 10 points).

- In the case of not passing the subject at the first opportunity:
1) The qualification of the Seminars and Laboratory Practices will be kept in the second opportunity in July, if it achieves a minimum of 5 points (out of 10).
2) The qualification of the Mixed Test of the second opportunity of July will replace the one obtained in the Mixed Test of the first opportunity, being again necessary to reach a minimum of 5 points (out of 10) in the score of the Mixed Test to be able to pass the matter.

- To obtain the qualification of not presented, the students may not have participated in more than 25% of the Laboratory Practices and Seminars, nor take the Mixed Test.

- In accordance with the academic regulations, the students who are evaluated in the "second opportunity", will only be able to opt for honorary enrollment if the maximum number of these for the course were not fully covered in the "first opportunity".

- For those students who take advantage of the

"recognition of part-time dedication or academic dispensation of exemption from attendance"

, we will try to adapt the schedules to their availability as far as possible. The final qualification for these students, both for the first and for the second opportunity, will follow the evaluation scheme described above.

- In the case of very exceptional, objectifiable and adequately justified circumstances, the Responsible Teacher could totally or partially exempt any member of the student body from attending the continuous assessment process. The students who had found themselves in this circumstance must pass a specific exam that leaves no doubt about the achievement of the competences of the subject.

Implications of plagiarism in the qualification:

The fraudulent completion of any exercise or test of the student for the
evaluation of the subject will be subject to disciplinary
responsibilities, as stated in the Regulations for Evaluation, Review
and Claim of University Degree and Master's Degree Qualifications
(Article 11) and in the Statute of the UDC Student Body (Article 35,
point 3): "Failed grade in the call in which the offense is committed:
the student will be graded with "Fail" (numerical grade 0) in the
corresponding call of the academic year, both the fault occurs both on
the first opportunity and on the second. For this, their qualification
will be modified in the first opportunity record if necessary".

Early call for December:

The weighting in the evaluation of the different teaching activities of the students who participate in the December call will be adapted to the new evaluation percentages included in this guide, in the event that these differ from each other in both the two academic years.

Learning outcomes	Study programme competences
Acquire basic knowledge related to molecular machines	A5	B1 B8	C8
Manage the main bibliographic sources in the field of molecular machines		B4 B8	C2 C3 C9
Develop the ability to expose and solve basic problems related to molecular machines and their applications	A4 A5 A7	B4 B5 B7 B10	C2 C3 C7 C9
Know various techniques for the synthesis, characterization and application of molecular machines	A4 A5 A7	B7 B8	C2
Interpret data from experimental observations	A7	B1 B4 B7 B8

Topic	Sub-topic
Topic 1. Biomolecular machines for the handling of information. polymerases and ribosomes	DNA and RNA polymerases and factors necessary for the correct synthesis. Messenger replacement. Riboswitches and LncRNAs, use of molecular tweezers in transcription studies. Protein synthesis. The canonical and non-canonical translation and translation modulation.
Topic 2. Biomolecular machines for transport, movement, transduction of signals and energy optimization	Transport and movement: transport proteins through microtubules and microfilaments. Obtaining energy: ATPases. Adjustment of electron transport chains to ATP synthesis. Signal transduction and molecular sensors.
Topic 3. Artificial biomolecular machines	Hybrid biomolecular systems. Membrane-bound hybrid molecular machines. DNA-based synthetic molecular machines.
Topic 4. Synthetic molecular machines for movement control	Catenanes. Rotaxanes. Molecular switches. Molecular pumps. Artificial muscles. Nanovalves. Nanomotors. Self-propelled devices.
Topic 5. Synthetic molecular machines with catalytic activity	Switchable catalysts. Artificial enzymes. Artificial ribosomes.
Topic 6. Synthetic molecular machines for the conversion, transport and storage of energy	Artificial photosynthetic devices. Energy nanocarriers. Energy nanoaccumulators.

Methodologies / tests	Competencies	Ordinary class hours	Student’s personal work hours	Total hours
Guest lecture / keynote speech	A5 B1	16	0	16
Events academic / information	A5 B1	3	0	3
Seminar	A5 A7 B1 B4 B5 B7 B8 B10 C2 C3 C7 C8 C9	4	20	24
Laboratory practice	A4 A5 A7 B1 B4 B5 B7 B8 B10 C2 C3 C7 C8 C9	10	10	20
Mixed objective/subjective test	B1 B4 B7 B8 C2	2	44	46

Personalized attention		3.5	0	3.5

(*)The information in the planning table is for guidance only and does not take into account the heterogeneity of the students.

Methodologies	Description
Guest lecture / keynote speech	Theoretical classes. Expository classes (use of blackboard, computer, cannon) complemented with the tools of virtual teaching
Events academic / information	Attendance at scientific and/or informative conferences
Seminar	Interactive sessions related to the subject, in which debates and exchange of opinions are established with the students
Laboratory practice	Carrying out experiments in the laboratory and elaboration of a practice report in which the results are described and the data obtained are analyzed
Mixed objective/subjective test	Completion of the different tests to verify the acquisition of knowledge (both theoretical and practical) and the acquisition of skills and attitudes

Methodologies	Competencies	Description	Qualification
Seminar	A5 A7 B1 B4 B5 B7 B8 B10 C2 C3 C7 C8 C9	Training activity of an eminently practical nature designed with the aim of influencing those aspects of the subject that are more difficult to understand. This activity will be evaluated through the active participation of the students.	30
Laboratory practice	A4 A5 A7 B1 B4 B5 B7 B8 B10 C2 C3 C7 C8 C9	During the laboratory practices, a continuous evaluation of the student's work will be carried out, the degree of understanding of the practices, the attitude and the rationalization of the experiments. Likewise, both the content and the format of the Laboratory Notebook will be evaluated.	40
Mixed objective/subjective test	B1 B4 B7 B8 C2	The mixed test will be carried out in the calendar agreed by the Faculty Board of each center. Its objective is to obtain an evaluation of the level of knowledge and competence reached by the student, as well as to evaluate the ability of the latter to relate them and to obtain an overview of the subject.	30

Assessment comments
- To pass the subject it will be necessary to achieve, added the qualifications of all the continuous evaluation activities (Seminars and Laboratory Practices), a minimum of 5 points (out of 10) and obtain a minimum of 5 points (out of 10) in the qualification of the mixed test. In the event that the students do not achieve the minimum score in any of them, if the sum of the set of all evaluable activities is greater than or equal to 5 points, the subject will appear as failed (4.5 out of 10 points). - In the case of not passing the subject at the first opportunity: 1) The qualification of the Seminars and Laboratory Practices will be kept in the second opportunity in July, if it achieves a minimum of 5 points (out of 10). 2) The qualification of the Mixed Test of the second opportunity of July will replace the one obtained in the Mixed Test of the first opportunity, being again necessary to reach a minimum of 5 points (out of 10) in the score of the Mixed Test to be able to pass the matter. - To obtain the qualification of not presented, the students may not have participated in more than 25% of the Laboratory Practices and Seminars, nor take the Mixed Test. - In accordance with the academic regulations, the students who are evaluated in the "second opportunity", will only be able to opt for honorary enrollment if the maximum number of these for the course were not fully covered in the "first opportunity". - For those students who take advantage of the *"recognition of part-time dedication or academic dispensation of exemption from attendance"* , we will try to adapt the schedules to their availability as far as possible. The final qualification for these students, both for the first and for the second opportunity, will follow the evaluation scheme described above. - In the case of very exceptional, objectifiable and adequately justified circumstances, the Responsible Teacher could totally or partially exempt any member of the student body from attending the continuous assessment process. The students who had found themselves in this circumstance must pass a specific exam that leaves no doubt about the achievement of the competences of the subject. Implications of plagiarism in the qualification: The fraudulent completion of any exercise or test of the student for the evaluation of the subject will be subject to disciplinary responsibilities, as stated in the Regulations for Evaluation, Review and Claim of University Degree and Master's Degree Qualifications (Article 11) and in the Statute of the UDC Student Body (Article 35, point 3): "Failed grade in the call in which the offense is committed: the student will be graded with "Fail" (numerical grade 0) in the corresponding call of the academic year, both the fault occurs both on the first opportunity and on the second. For this, their qualification will be modified in the first opportunity record if necessary". Early call for December: The weighting in the evaluation of the different teaching activities of the students who participate in the December call will be adapted to the new evaluation percentages included in this guide, in the event that these differ from each other in both the two academic years.

Basic	Erbas-Cakmak, Sundus; Leigh, David A.; McTernan, Charlie T.; Nussbaumer, Alina L. (2015). Artificial Molecular Machines. American Chemical Society Steven, Alasdair; Baumeister, Wolfgang; Johnson, Louise N.; Perham, Richard N. (2016). Molecular Biology of Assemblies and Machines. Garland Science Lodish, Harvey; Berk, Arnold; Kaiser, Chris A.; Krieger, Monty; Bretscher, Anthony (2021). Molecular Cell Biology. W H Freeman & Co Balzani, Vincenzo; Credi, Alberto; Venturi, Marguerita (2008). Molecular Devices and Machines: Concepts and Perspectives for the Nanoworld. Wiley-VCH Credi, Alberto; Balzani, Vincenzo (2020). Molecular Machines. 1088press
	Selected scientific articles related to the subject's agenda.
Complementary	Credi, Alberto; Silvi, Serena; Venturi, Margherita (2014). Molecular Machines and Motors - Recent Advances and Perspectives. Springer Zocchi, Giovanni (2018). Molecular Machines: A Materials Science Approach. Princeton University Press
	Selected scientific articles related to the subject's agenda.