Student's
work will be continuously evaluated through attendance at assessable
activities, participation in seminars, solving resolution questions and
problems, laboratory practices and a mixed test. To make the most of the
course, students must attend all face-to-face activities.

Completing
the laboratory practices is mandatory for passing the course. Students who do
not complete ALL the practices, without proper justification, will not be able
to pass the course, regardless of their weight in the evaluation.

FIRST
CHANCE: to pass the subject it is necessary to obtain a minimum grade of 4.5 (out
of 10) in the mixed objective text. The final grade is obtained by applying the established percentages and
the previously established restrictions, being necessary a final grade equal or
higher than 5 (out of 10).

The student
will obtain the grade of Not Presented when he/she does not take either the
laboratory practices or the mixed test.

SECOND
CHANCE: in the second opportunity the mixed test will be taken, whose grade
will replace the grade obtained in the first opportunity, maintaining the
grades of the laboratory practicals and seminars in the first opportunity. The
final grade is obtained by applying the established percentages and the
previously established restrictions, being necessary a final grade equal or
higher than 5 (out of 10). Students evaluated in the second opportunity will only
be eligible for the honor registration if the maximum number of these for the
corresponding course were not covered in their totality in the first
opportunity.

ADVANCED
CALL: the mixed test will be carried out, whose qualification will replace the
one obtained in the last course, maintaining the grades of the rest of the
evaluable activities. The final grade will be obtained taking into account the
percentages of the current course.

In any
case, if a minimum grade of 4.5/10 is not reached in each of the evaluable parts,
the course will be failed, even if the final grade, calculated according to the
corresponding percentages, is equal or higher than 5/10. In this case, the
final grade will be 4.5/10.

HONOR
ENROLLMENT: Students evaluated in the
second opportunity will only be eligible for the MH if the number of MHs was
not covered in its totality in the first opportunity.

All aspects related to “academic dispensation”,
“dedication to study”, “permanence” and “academic fraud” will be governed in
accordance with the current academic regulations of the UDC.

Learning outcomes	Study programme competences / results
Recognize the main applications of biotechnology	A3	B3 B4 B7	C3
Identify the main tools of Molecular Biology, metabolic engineering, protein engineering and cell and tissue engineering.	A1 A3	B3 B4 B7
Apply the main biotechnological techniques	A6 A8	B3 B4 B8	C3 C7 C8
Solve basic biotechnology problems	A3 A6 A7	B3 B4 B6 B7 B8	C3 C7 C8
Recognize and apply ethical and legal principles in the field of Biotechnology	A10	B3 B4 B8	C8

Topic	Sub-topic
1. INTRODUCTION TO BIOTECHNOLOGY	Current concept of Biotechnology. History and development of Biotechnology. Outlook. Importance of Nanobiotechnology. Situation of biotechnology in Spain.
2. CLONING	2.1. Introduction to gene cloning 2.2. Steps in gene cloning 2.3. Polymerase chain reaction 2.4. Cloning and nanotechnology
3. GENOMIC LIBRARIES	3.1. Gene libraries 3.2. Metagenomics 3.3. Gene libraries and nanotechnology
4. PROTEIN ENGINEERING	4.1. Production of heterologous proteins in bacteria and yeast 4.2. Production of heterologous proteins in mammalian cells 4.3. Protein engineering
5. PROTEIN INMOBILIZATION	5.1. Introduction to immobilization 5.2. Immobilization systems 5.3. Nanoscale immobilization
6. CELL AND TISSUE ENGINEERING	6.1. Introduction to plant cultures 6.2. Micropropagation. Stages and types 6.3. Calluses and cell suspensions 6.4. Current applications of plant cell and tissue culture
7. GENETIC MODIFICATION	7.1. Domestication 7.2. Genetic improvement and induced mutagenesis 7.3. Genetic transformation 7.4. Gene editing
8. BIOREMEDIATION AND BIOSENSING	8.1. Bioremediation 8.2. Biosensing 8.3. Examples of actions in bioremediation
9. ETHICAL AND LEGAL ASPECTS	9.1. Regulatory regulations 9.2. Ethical aspects 9.3. Social perception

Methodologies / tests	Competencies / Results	Teaching hours (in-person & virtual)	Student’s personal work hours	Total hours
Laboratory practice	A3 A6 A7 A8 B3 B4 B6 B7 C3 C7	15	5	20
Document analysis	A1 A10 B3 B4 C7 C8	6	8	14
Mixed objective/subjective test	A1 A3 A7 B3 B4	2	10	12
Guest lecture / keynote speech	B3 B6 B8 C8	28	70	98

Personalized attention		6	0	6

(*)The information in the planning table is for guidance only and does not take into account the heterogeneity of the students.

Methodologies	Description
Laboratory practice	A series of activities will be carried out in the practice laboratory, so that students learn to handle basic scientific instruments used in biotechnology.
Document analysis	Directed activity of group work that will be carried out during the interactive group classes. Students will analyze various documentary sources and must prepare texts or audiovisual materials individually or in small groups.
Mixed objective/subjective test	Written test used to assess learning and that can combine different types of questions: multiple choice, association, explanatory or calculation questions and problem solving.
Guest lecture / keynote speech	The contents of the subject will be taught by the teachers. The presentations and other documentation will be made available to the students on the Virtual Campus platform.

Methodologies	Competencies / Results	Description	Qualification
Document analysis	A1 A10 B3 B4 C7 C8	Evaluation in which the work during the interactive group sessions and the materials delivered by the student will be taken into account (quality of the works, discussion capacity, use of correct scientific language and verified bibliographic information).	30
Mixed objective/subjective test	A1 A3 A7 B3 B4	Assessment of theoretical knowledge	50
Laboratory practice	A3 A6 A7 A8 B3 B4 B6 B7 C3 C7	Laboratory practices are considered a MANDATORY attendance activity to pass the subject. A test will be carried out to evaluate the acquired knowledge.	20

Assessment comments
Student's work will be continuously evaluated through attendance at assessable activities, participation in seminars, solving resolution questions and problems, laboratory practices and a mixed test. To make the most of the course, students must attend all face-to-face activities. Completing the laboratory practices is mandatory for passing the course. Students who do not complete ALL the practices, without proper justification, will not be able to pass the course, regardless of their weight in the evaluation. FIRST CHANCE: to pass the subject it is necessary to obtain a minimum grade of 4.5 (out of 10) in the mixed objective text. The final grade is obtained by applying the established percentages and the previously established restrictions, being necessary a final grade equal or higher than 5 (out of 10). The student will obtain the grade of Not Presented when he/she does not take either the laboratory practices or the mixed test. SECOND CHANCE: in the second opportunity the mixed test will be taken, whose grade will replace the grade obtained in the first opportunity, maintaining the grades of the laboratory practicals and seminars in the first opportunity. The final grade is obtained by applying the established percentages and the previously established restrictions, being necessary a final grade equal or higher than 5 (out of 10). Students evaluated in the second opportunity will only be eligible for the honor registration if the maximum number of these for the corresponding course were not covered in their totality in the first opportunity. ADVANCED CALL: the mixed test will be carried out, whose qualification will replace the one obtained in the last course, maintaining the grades of the rest of the evaluable activities. The final grade will be obtained taking into account the percentages of the current course. In any case, if a minimum grade of 4.5/10 is not reached in each of the evaluable parts, the course will be failed, even if the final grade, calculated according to the corresponding percentages, is equal or higher than 5/10. In this case, the final grade will be 4.5/10. HONOR ENROLLMENT: Students evaluated in the second opportunity will only be eligible for the MH if the number of MHs was not covered in its totality in the first opportunity. All aspects related to “academic dispensation”, “dedication to study”, “permanence” and “academic fraud” will be governed in accordance with the current academic regulations of the UDC.

Basic	Tzfira, T. e Citovsky, V. (2006). Agrobacterium-mediated genetic transformation of plants: biology and biotechnology. Curr. Opin. Biotechnol. 17:147–154. Benítez Burraco, A (2005). Avances recientes en Biotecnología vegetal e ingeniería genética de plantas. Editorial Reverté. Taji, A., Kumar, P., Lakshmanan, P. (2002). In vitro plant breeeding. Ed. Food Products Press. Niemeyer, C.M., Mirkin, C.A. (2004). Nanobiotechnology Concepts, Applications and Perspectives. Wiley Omran, B. (2020). Nanobiotechnology: A Multidisciplinary Field of Science. Springer Basra, A.S. (2000). Plant growth regulators in agriculture and horticulture. Their role and commercial uses. Ed. Food Products Press.

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