Competencies / Study results |
Code
|
Study programme competences / results
|
A1 |
CE1 - Comprender los conceptos, principios, teorías y hechos fundamentales relacionados con la Nanociencia y Nanotecnología. |
A2 |
CE2 - Aplicar los conceptos, principios, teorías y hechos fundamentales relacionados con la Nanociencia y Nanotecnología a la resolución de problemas de naturaleza cuantitativa o cualitativa. |
A9 |
CE9 - Evaluar correctamente los riesgos sanitarios y de impacto ambiental asociados a la Nanociencia y la Nanotecnología. |
A10 |
CE10 - Comprender la legislación en el ámbito del conocimiento y la aplicación de la Nanociencia y Nanotecnología. Aplicar principios éticos en este marco. |
B3 |
CB3 - Que los estudiantes tengan la capacidad de reunir e interpretar datos relevantes (normalmente dentro de su área de estudio) para emitir juicios que incluyan una reflexión sobre temas relevantes de índole social, científica o ética |
B4 |
CB4 - Que los estudiantes puedan transmitir información, ideas, problemas y soluciones a un público tanto especializado como no especializado |
B8 |
CG3 - Aplicar un pensamiento crítico, lógico y creativo. |
B11 |
CG6 - Comportarse con ética y responsabilidad social como ciudadano/a y como profesional. |
B12 |
CG7 - Comunicarse de manera efectiva en un entorno de trabajo. |
C4 |
CT4 - Desarrollarse para el ejercicio de una ciudadanía respetuosa con la cultura democrática, los derechos humanos y la perspectiva de género |
C5 |
CT5 - Entender la importancia de la cultura emprendedora y conocer los medios al alcance de las personas emprendedoras |
C6 |
CT6 - Adquirir habilidades para la vida y hábitos, rutinas y estilos de vida saludables |
C7 |
CT7 - Desarrollar la capacidad de trabajar en equipos interdisciplinares o transdisciplinares, para ofrecer propuestas que contribuyan a un desarrollo sostenible ambiental, económico, político y social. |
C8 |
CT8 - Valorar la importancia que tiene la investigación, la innovación y el desarrollo tecnológico en el avance socioeconómico y cultural de la sociedad |
Learning aims |
Learning outcomes |
Study programme competences / results |
Synthesise, prepare and characterise biomaterials for use in nanomedicine |
A1 A2 A9
|
B3 B4 B8 B12
|
C5 C7 C8
|
To know the structural characteristics of materials and the main techniques for their identification and characterisation |
A1 A2 A9
|
B3 B4 B12
|
C5 C7 C8
|
Operate laboratory instrumentation and equipment for chemical, physical and biological experiments at the nanoscale |
A1 A2 A9
|
B3 B4 B8 B12
|
C5 C7 C8
|
Interpret data obtained from experimental data using specific software tools |
A1 A2 A9
|
B3 B4 B8 B12
|
C5 C7 C8
|
Understand and evaluate legislation in the field of knowledge and application of Nanoscience and Nanotechnology in medicine. Apply ethical principles in this framework |
A1 A2 A9 A10
|
B3 B4 B11 B12
|
C4 C5 C6 C7 C8
|
Contents |
Topic |
Sub-topic |
Topic 1. Concept of nanomedicine |
Nanoparticles in biological environments, biocompatibility, stability and aggregation. Functionalisation of nanomaterials and their application to nanomedicine. Routes of administration of nanomaterials, advances and drawbacks and obstacles to overcome. Cellular traffic. Biological barriers. Smart nanomaterials: applications in therapy and diagnostics... Nanomaterials and immune response |
Topic 2. Nanodiagnosis in vitro: nanosensors and integrated devices |
Nanodiagnosis: Introduction to medical diagnosis. Biosensors and integrated devices of medical interest. Biosensors: definition, characteristics and applications. Bioreceptors and analytical nanodevices. Biomarkers. Diagnostic techniques based on immunoassay (Dot blot, Western blot, ELISA, flow cytometry, laminar flow). Diagnostic techniques based on plasmonic sensors (SERS, SEF, FRET). |
Topic 3. Nanodiagnosis in vivo: diagnostic imaging |
Basic fundamentals of the different medical imaging techniques: Ultrasound, Magnetic Resonance Imaging, Computed Tomography. Positron Emission Tomography, Contrast Agents. Comparison of the different imaging modalities. |
Topic 4. Tissue nanotechnology. Nanofabrication and characterisation of scaffolds |
Gels and self-assembled systems. Composites. Supercritical fluids and aerogels. Electrospinning and bioprinting. Tissue engineering. Introduction to regenerative medicine: regeneration processes, fibrosis, scaffolding vs. implant. Cell modulation through biomechanics, cell adhesion, roughness and nanostructure. Active substance delivery systems with application in regenerative medicine: conventional drug delivery systems, sustained release of proteins, gene therapies. |
Topic 5. Nanosurgery |
Nanotechnology for haemostasis during surgery. Catheters with biosensors for minimally invasive surgery. Nanoscale surgery. Nanorobotics for surgery. |
Topic 6. Nanotoxicology |
Topic 6. Nanotoxicology. Toxicity of nanoparticles. Blood compatibility. Routes of exposure. Accumulation and deposition of nanoparticles in tissues. Measures to reduce nanoparticle toxicity. Environmental effects of nanoparticles. FDA e EMA regulation of nanobiotechnology products. |
Topic 7. Ethical and legal aspects |
Ethical and legal aspects in Nanotechnology in Medicine |
Planning |
Methodologies / tests |
Competencies / Results |
Teaching hours (in-person & virtual) |
Student’s personal work hours |
Total hours |
Laboratory practice |
A9 B3 B4 B8 B11 B12 C7 |
10 |
20 |
30 |
Supervised projects |
A2 A10 B3 B4 B8 B11 B12 C4 C7 |
7 |
14 |
21 |
Mixed objective/subjective test |
A1 A2 A9 A10 B3 B8 C8 |
5.5 |
0 |
5.5 |
Guest lecture / keynote speech |
A1 A2 A9 A10 C5 C6 C8 |
18 |
36 |
54 |
|
Personalized attention |
|
2 |
0 |
2 |
|
(*)The information in the planning table is for guidance only and does not take into account the heterogeneity of the students. |
Methodologies |
Methodologies |
Description |
Laboratory practice |
Development of techniques of current use in nanoscience research in medicine, complementing the knowledge imparted in the master session. |
Supervised projects |
Final activity reflecting the theoretical and methodological mastery of the subject. |
Mixed objective/subjective test |
Mixed test used for the assessment of learning. |
Guest lecture / keynote speech |
The topics of the subject will be taught by the lecturers with the help of audiovisual aids. The relevant documentation will be made available to students on the Virtual Campus. |
Personalized attention |
Methodologies
|
Supervised projects |
Laboratory practice |
|
Description |
Laboratory practice. For students, personalised tutorials will be provided, focusing on guidance for problem solving, resolving doubts and clarifications. This personalised attention will be carried out throughout the course and upon request of the students.
Supervised projects. Students may also request personalised direct and/or virtual tutorials and resolve specific doubts by e-mail. |
|
Assessment |
Methodologies
|
Competencies / Results |
Description
|
Qualification
|
Mixed objective/subjective test |
A1 A2 A9 A10 B3 B8 C8 |
Proba que pode integrar preguntas tipo de probas de ensaio e preguntas tipo de probas obxectivas.
En canto a preguntas de ensaio, recolle preguntas abertas de desenvolvemento. Ademais, en canto preguntas obxectivas, pode combinar preguntas de resposta múltiple, de ordenación, de resposta breve, de discriminación, de completar e/o de asociación. múltiple. |
60 |
Supervised projects |
A2 A10 B3 B4 B8 B11 B12 C4 C7 |
O alumnado levará a cabo un traballo en grupos ou individualmente e presentación oral relacionados con algún tema da materia. |
25 |
Laboratory practice |
A9 B3 B4 B8 B11 B12 C7 |
As prácticas de laboratorio considéranse unha actividade de asistencia obrigatoria para superar a materia. A avaliación dos coñecementos adquiridos avaliarase por unha memoria de prácticas desenvolvida polo alumnado. |
15 |
|
Assessment comments |
LABORATORY PRACTICES are mandatory. Absence from practicals must be duly justified in order to pass the subject. First and second chance: In order to pass the subject a 5 must be obtained in the mixed test. If the qualification resulting from the sum of all the evaluable activities is equal to or higher than 5, but the indicated requirement is not met, the qualification will be 4.0 (fail). The mixed test may consist of any of the following and/or a combination of several: Essay questions: open-ended essay questions, multiple-choice questions (one or more of the answers may be true), ranking questions, short answer questions, discrimination questions, fill-in-the-blank questions, association questions. It is considered as Not Presented (NP) when the student does not take the test in the official evaluation period. Plagiarism and the use of non-original material, including material obtained from the internet, without express indication of its origin and, if applicable, the permission of its author, will be graded with a fail (0.0) in the activity. If a student copies during an exam, this will result in a fail (0.0) in the subject in the corresponding exam session. Grading system: Numerical from 0 to 10, with 10 being the highest mark and 5 a pass. The qualification system will be expressed by numerical qualification in accordance with the provisions of art. 5 of Royal Decree 1125/2003 of 5 September (BOE 18 September), which establishes the European credit system and the qualification system for official university degrees valid throughout the national territory. Grading system: 0-4.9=Suspenso, 5-6.9=Aprobado, 7-8.9=Notable, 9-10=Sobresaliente, 9-10 Matrícula de Honor (Graciable). Honours will be awarded preferentially to students who achieve a grade equal to or higher than 9 at the first opportunity (January). In the case of part-time students who are exempt from attendance, additional measures may be adopted to enable them to pass the subject, such as flexibility in the deadline for submitting assignments, flexibility in the timetable for practicals or the performance of a global test to assess the learning outcomes. Fraudulent performance in the assessment tests or activities, once verified, will directly lead to a failing grade of "0" in the subject at the corresponding time. All aspects related to "academic dispensation", "dedication to study", "permanence" and "academic fraud" shall be governed in accordance with the current academic regulations of the UDC (https://www.udc.es/es/normativa/academica/).
|
Sources of information |
Basic
|
Alexandru Mihai Grumezescu (2017). Nano- and Microscale Drug Delivery Systems. "Design and Fabrication". Elsevier
Yi Ge, Songjun Li, Shenqi Wang, Richard Moore (2014). Nanomedicine: Principles and Perspectives "Nanostructure Science and Technology". Springer
A Villaverde (2011). Nanoparticles in translational science and medicine. "Progress in Molecular Biology and Translational Science". Elsevier
Dimitrios P. Nikolelis and Georgia-Paraskevi Nikoleli (2018). Nanotechnology and biosensors. Elsevier |
|
Complementary
|
(). Center for Cancer Nanotechnology Excellence and Translation, Stanford University. http://nano.cancer.gov/action/programs/stanford/
(). Links to the European Technology Platform for Nanomedicine. http://www.etp-nanomedicine.eu/public.
(). The International Association of Nanotechnology . http://www.ianano.org |
|
Recommendations |
Subjects that it is recommended to have taken before |
Techniques of Characterisation of Nanomaterials 2/610G04030 | Techniques of Characterisation of Nanomaterials 1/610G04025 | Synthesis and Preparation of Nanomaterials/610G04020 | Molecular and Metabolic Biochemistry/610G04023 | Cell Biology/610G04003 | Integrated Basic Laboratory/610G04004 |
|
Subjects that are recommended to be taken simultaneously |
Molecular Machines/610G04036 |
|
Subjects that continue the syllabus |
Nanotechnology in Pharmacy/610G04043 | Nanofabrication/610G04040 |
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Other comments |
Recommendations Sustainability Environment, People and Gender Equality. To help achieve an immediate sustainable environment and comply with the objective of action number 5: "Healthy, environmentally and socially sustainable teaching and research" of the "Green Campus Action Plan of the Faculty of Science". 1.- The delivery of the documentary work to be carried out in this subject will be done through Moodle, in digital format without the need to print them. 2.- The importance of ethical principles related to the values of sustainability in personal and professional behaviour must be taken into account. 3. The full integration of students who, for physical, sensory, mental or socio-cultural reasons, experience difficulties in gaining suitable, equal and beneficial access to university life will be facilitated. 4. Work will be carried out to identify and modify sexist prejudices and attitudes, and the environment will be influenced in order to modify them and promote values of respect and equality. Likewise, if adverse gender-based situations are identified, measures will be taken to correct them. 5. It is understood that university students must have acquired language skills in relation to oral and written expression. Therefore, spelling (spelling, accentuation and punctuation), grammatical and lexical correctness in assignments and exams will be essential and compulsory in order to pass the subject. |
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