| Study programme competencies |
| Code | Study programme competences |
| A1 | Skills of using usual techniques and instruments in the cellular, biological and molecular research: that are able to use techniques and instruments as well as understanding potentials of their uses and applications. |
| A2 | Skills of working in a sure way in the laboratories knowing operation handbooks and actions to avoid incidents of risk. |
| A6 | Skills of understanding the functioning of cells through the structural organization, biochemistry, gene expression and genetic variability. |
| A7 | Skills of knowing and analyzing specific cellular systems as stem cells, nerve cells, cells of the immune system, or other cells related to several pathologies. |
| A13 | Skills to become a professional in health, pharmacy, veterinary, animal production, biotechnology or food sectors. |
| B5 | Correct oral and written communication on scientific topics in the native language and at least in another International diffusion language. |
| B9 | Skills of preparation, show and defense of a work. |
| C1 | Adequate oral and written expression in the official languages. |
| Learning aims | |||
| Learning outcomes | Study programme competences | ||
| Skills of understanding the functioning of cells through the structural organization. | AR6 AR7 |
BR5 BR9 |
CC1 |
| Skills to apply immunohistochemical techniques to the study of cell components | AR1 AR2 AR13 |
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| Contents |
| Topic | Sub-topic |
| Introduction to cell | Cell Domains and the origin of multicellularity. Integrative view of the eukaryote cell |
| Structure and dynamics of the cell nucleus | Structure of nuclear envelope Nucleocytoplasmic traffic. Cell nucleus organization: chromatinic territories and nuclear subdomains. |
| Biogenesis, trafficking and functions of the cell endomembrane system | Structure and membrane domains. Membrane compartments and vesicular trafficking. Traffic RE-Golgi complex. Endosomes and endocytosis. Traffic between the Golgi complex and endosomes. The secretory pathway of the Golgi complex: conventional and unconventional exocytosis. Lipid trafficking between compartments. Post-translational targeting of cytosolic proteins to organelles. Degradation of cellular components. |
| Cytoskeleton and cell dynamic. | Microtubules and associated proteins. Microtubule complex structures. Microfilaments and associated proteins. Cell motility and contractile systems. Cytoskeleton and cytokinesis. Intermediate filaments. Septins. |
| Interactions cell to cell and cell to extracellular matrix | Cell adhesion and junctions Extracellular matrix molecules Pathological alterations of the extracellular matrix. |
| Planning | ||||
| Methodologies / tests | Competencies | Ordinary class hours | Student’s personal work hours | Total hours |
| Guest lecture / keynote speech | A6 A7 | 8 | 16 | 24 |
| Document analysis | A6 A13 B5 B9 C1 | 4 | 12 | 16 |
| Laboratory practice | A1 A2 | 10 | 20 | 30 |
| Mixed objective/subjective test | A6 | 2.5 | 0 | 2.5 |
| Personalized attention | 1 | 0 | 1 | |
| (*)The information in the planning table is for guidance only and does not take into account the heterogeneity of the students. | ||||
| Methodologies |
| Methodologies | Description |
| Guest lecture / keynote speech | Face sessions of approximately 60 minutes on the contents of the program. For a full exploitation of these sessions, it is recommended that students have previously read on their own fundamental aspects of these topics in the recommended texts. |
| Document analysis | It will consist of individual reading of recent research articles or reviews in Cell Biology designated by the lecturer complementing the given lectures. In classroom sessions each student will present a brief summary in limited time and will provide the basis for a posterior general discussion. |
| Laboratory practice | It will consist of the application of immunohistochemical methods for the analysis and study of certain cellular structures or components. |
| Mixed objective/subjective test | It will consist of an exam with choice questions and/or short questions on the contents of the topic treated in lectures and seminars. |
| Personalized attention |
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| Assessment | |||
| Methodologies | Competencies | Description | Qualification |
| Document analysis | A6 A13 B5 B9 C1 | The degree of understanding of the subject and its presentation in the indicated time so as original graphical abstract will be assessed. Active participation in the discussion of presentations is also valued. | 30 |
| Mixed objective/subjective test | A6 | It will consist of short answer and multiple choice questions on the contents of the topics covered in the keynote sessions and seminars. | 70 |
| Assessment comments | |||
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Part time students may substitute attendance of seminars (Journal Exceptionally, In the second call (July) only the results of the examination will be Part time students could make their exams presentially or on line (via moodle or skype). Honors will be preferably granted among students presented in the first call. |
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| Sources of information |
| Basic |
Pollard, T.D; Earnshaw WC (2002, 2008). Cell Biology. Saunders
Alberts, B.; Johnson A.; Lewis, J.; Raff, M.; Roberts, R. & Walter, P (2008). Molecular Biology of the cell. Garland |
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| Complementary |
Lodish, H.; Berk, A.; Zypursky, S.; Matsudaira, P.; Baltimore, D.; Darnell, J. (2013). Molecular cell biology. Macmillan |
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Enlaces de interés/ Links of interest: |
| Recommendations | |
| Subjects that it is recommended to have taken before |
| Subjects that are recommended to be taken simultaneously |
| Subjects that continue the syllabus |
| Other comments | |