Identifying Data 2020/21
Subject (*) Advanced Sample Preparation Techniques Code 610509324
Study programme
Mestrado Universitario en Investigación Química e Química Industrial (Plan 2020)
Descriptors Cycle Period Year Type Credits
Official Master's Degree 1st four-month period
 First Optional 3
Language
Spanish
Teaching method Face-to-face
Prerequisites
Department Departamento profesorado máster
Química
Coordinador
Alonso Rodriguez, Elia
 E-mail
elia.alonso@udc.es
Lecturers
Alonso Rodriguez, Elia
 E-mail
elia.alonso@udc.es
Web http://www.usc.es/gl/centros/quimica/curso/master.html
General description Esta materia céntrase en capacitar ao alumno para obter un coñecemento pormenorizado e actual de distintos aspectos teóricos e prácticos, relacionados coas técnicas de preparación de mostra (métodos de extracción, purificación e concentración) utilizadas nos métodos de análises.
Contingency plan 1. Modificacións nos contidos
Non se realizan cambios
2. Metodoloxías
*Metodoloxías docentes que se manteñen
Mantéñense todas as metodoloxías e se a situación sanitaria o require, adaptaranse ao modo non presencial a través de Moodle e Teams.
*Metodoloxías docentes que se modifican
Non hay modificacions
3. Mecanismos de atención personalizada ao alumnado
Titorías por Teams, Moodle e correo electrónico
4. Modificacións na avaliación
Non se realizan cambios
*Observacións de avaliación:
Mantense o sistema de evaluación e os porcentaxes
5. Modificacións da bibliografía ou webgrafía
Non se realizan cambios

Study programme competencies
Code Study programme competences
A2 Suggest alternatives for solving complex chemical problems related to the different areas of chemistry.
A6 Design processes involving the treatment or disposal of hazardous chemicals
A7 Operate with advanced instrumentation for chemical analysis and structural determination.
A9 Promote innovation and entrepreneurship in the chemical industry and in research.
B2 Students should apply their knowledge and ability to solve problems in new or unfamiliar environments within broader (or multidisciplinary) contexts related to their field of study.
B4 Students should be able to communicate their conclusions, and the knowledge and the reasons that support them to specialists and non-specialists in a clear and unambiguous manner
B5 Students must possess learning skills to allow them to continue studying in a way that will have to be largely self-directed or autonomous.
B7 Identify information from scientific literature by using appropriate channels and integrate such information to raise and contextualize a research topic
B10 Use of scientific terminology in English to explain the experimental results in the context of the chemical profession
B11 Apply correctly the new technologies to gather and organize the information to solve problems in the professional activity.
C1 CT1 - Elaborar, escribir e defender publicamente informes de carácter científico e técnico
C3 CT3 - Traballar con autonomía e eficiencia na práctica diaria da investigación ou da actividade profesional.
C4 CT4 - Apreciar o valor da calidade e mellora continua, actuando con rigor, responsabilidade e ética profesional.

Learning aims
Learning outcomes Study programme competences
Define concepts, principles, theories and applications of different sample preparation techniques AC2
Propose alternatives to the traditional extraction techniques for solving complex chemical problems AC7
Apply advanced extraction processes in innovative fields of industry and chemical research BC2
Innovate in sample preparation methods used in chemical analysis in different areas of chemistry AC9
Assess risks and environmental impacts of new sample preparation techniques against conventional techniques, proposing "Green Analytical Chemistry" alternatives AC2
AC6
Analyze and discuss examples of applications using the knowledge acquired, including primary literature sources and scientific databases (SciFinder, WOK, Medline, etc.) BC4
BC7
Promote innovation in industry and in chemical research AC9
 BC5
BC10
BC11
 CC4
Employ of advanced instrumentation for chemical analysis AC7
Work and learn independently and with initiative CC3
Write and present scientific and technical reports CC1

Contents
Topic Sub-topic
Unit 1. Introduction to advanced sample preparation techniques. - Importancia da etapa de preparación de mostra.
- Técnicas clásicas de extracción.
- Tratamento enzimático de mostra.
- Tendencias na etapa de preparación de mostra.
- Sistemas de mostraxe pasiva.
- Mostraxe activa de aire e partículas.
Unit 2. Supercritical fluid extraction. - Propiedades xerais dos fluídos supercríticos.
- Instrumentación: compoñentes básicos dun extractor de FS.
- Modos de extracción: métodos on-line e off-line.
- Aplicacións.
Unit 3. Microwave assisted extraction. - Fundamentos teóricos.
- Transformación da enerxía de microondas en calor.
- Extracción con disolventes de alta perda dieléctrica.
- Extracción con disolventes transparentes á radiación.
- Instrumentación.
- Aplicacións.
Unit 4. Accelerated solvent extraction. - Fundamento.
- Instrumentación.
- Modo de operación.
- Aplicacións.
Unit 5. Solid phase extraction. - Fundamento.
- Tipos de fases sólidas.
- Desenvolvemento de métodos.
- Automatización da extracción en fase sólida.
- Microextracción con adsorbentes empaquetados (MEPS).
- Extracción en fase sólida dispersiva (dSPE, QuEChERS).
- Dispersión da matriz nunha fase sólida (MSPD).
Unit 6. Solid phase microextraction. - Introdución.
- Principios básicos.
- Modos de extracción.
- Tipos de recubrimientos.
- Parámetros que afectan o proceso de extracción.
- Cuantificación.
- Aplicacións.
Unit 7. Liquid phase microextraction. - Microextracción con pinga suspendida (Single-drop microextraction, SDME).
- Técnicas de membrana (Membrane Assisted Solvent Extraction, MASE).
- Microextracción con fibra oca (Hollowfiber-LPME)
- Microextracción en fase líquida dispersiva (Dispersive liquid-liquid microextraction, DLLME).
- Microextracción dispersiva asistida por ultrasóns (Ultrasound-Assisted Emulsification-Microextraction, USAEME)

Planning
Methodologies / tests Competencies Ordinary class hours Student’s personal work hours Total hours
Guest lecture / keynote speech A2 A9 12 18 30
Seminar A2 A6 A7 B2 B4 B5 B7 B10 B11 C1 C3 C4 7 28 35
Mixed objective/subjective test A2 A6 B2 2 6 8
 
Personalized attention 2 0 2
 
(*)The information in the planning table is for guidance only and does not take into account the heterogeneity of the students.

Methodologies
Methodologies Description
Guest lecture / keynote speech Nelas abordaranse os fundamentos teóricos e instrumentais de cada unha das técnicas de preparación de mostra. Proxectaranse diapositivas, e nalgúns casos utilizaranse animacións informáticas ou algún vídeo, que facilitarán o seguimento das explicacións. Durante a presentación dos distintos temas iranse formulando preguntas ao fío dos conceptos explicados co obxecto de dinamizar as clases e fomentar a participación.
Seminar Sesións realizadas con profesorado propio do Máster, ou con profesionais convidados da empresa, a administración ou doutras universidades. Resolución de casos prácticos (problemas, cuestiones tipo test, interpretación e procesamento da información, avaliación de publicacións científicas, etc.). Ademais, utilizarase algunha das clases de seminario para que os alumnos presenten os traballos expostos nalgún dos temas e para poder discutilos en grupo.
Mixed objective/subjective test Proba escrita utilizada para a avaliación da aprendizaxe do alumno.

Personalized attention
Methodologies
Seminar
Description
During the seminar sessions an individualized learning control of the students will be held and their questions will be resolved.

Students being recognized officially as partial-time and entitled not to attend the lectures will be attended in a tutorships regime (set hour with teacher in advance).



Assessment
Methodologies Competencies Description Qualification
Seminar A2 A6 A7 B2 B4 B5 B7 B10 B11 C1 C3 C4 Resolución de problemas e/ou casos prácticos (10%)
Realización de traballos e informes escritos (10%)
Exposición oral (traballos, informes, problemas e casos prácticos) (10%)
Avaliación continua do interese e actitude do alumno mediante preguntas e cuestións durante o curso (10%) 		40
Mixed objective/subjective test A2 A6 B2 Realizarase un exame final que versará sobre a totalidade dos contidos da materia. 60
 
Assessment comments
<p>- To be examined it is necessary to have attended 80% of the seminar classes and personalized attention.</p><p>- Continuous assessment (N1) represent 40% of the final grade and will consist of seminar sessions and personalized attention which will include:</p><p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; . Solving questions and/or case studies: 10%</p><p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; . Carrying out papers and reports: 10%</p><p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; . Oral presentation: 10%</p><p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; . Questions along the course: 10%</p><p>- The final exam (N2) will cover the entire contents of the subject.</p><p>- Student's final grade will be obtained applying the following formula:</p><p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;&nbsp; &nbsp; Final grade = 0,4 x N1 + 0,6 x N2&nbsp;&nbsp;&nbsp;&nbsp; &nbsp;&nbsp; &nbsp; N1 (0-10 points)&nbsp; N2 (0-10 points)</p><p>- Students who fail the course must attend all classes again.</p><p>For students being recognized officially as partial-time and entitled not to attend the lectures, the final exam represent 80% of the final grade and supervised projects 20%.</p><p>&nbsp;</p>

Sources of information
Basic Pawliszyn, J. (Ed.) (2012). Comprehensive Sampling and Sample Preparation. Elsevier

Complementary Luque de Castro, M.D.; Luque García, J.L. (2002). Aceleration and Automation of Solid Sample Treatment. Elsevier
Fritz, J.S. (1999). Analytical Solid-Phase Extraction. Wiley-VCH
Pawliszyn, J. (Ed.) (1999). Aplications of Solid Phase Microextraction. RSC Chromatography Monographs
Self, R. (2005). Extraction of Organic Analytes from Foods. The Royal Sociaty of Chemistry (RSC)
Dean, J.R. (Ed.) (2009). Extraction Techniques in Analytical Sciences. Wiley
Pawliszyn, J.; Lord, H.L. (Ed.) (2010 ). Handbook of Sample Preparation. Wiley
Mitra, S. (Ed.) (2003). Sample Preparation Techniques in Analytical Chemistry. Wiley
Scheppeers Wercinski, S.A. (Ed.) (1999). Solid Phase Microextraction. A Practical Guide. Marcel Dekker Inc.
Pawliszyn, J. (1997). Solid Phase Microextraction. Theory and Practice. Wiley-VCH
Kokosa, J.M.; Przyjazny, A.; Jeannot, M.A. (2009). Solvent Microextraction. Wiley
Cela, R.; Lorenzo, R.A.; Casais, C. (2002). Técnicas de Separación en Química Analítica. Síntesis


Recommendations
Subjects that it is recommended to have taken before

Subjects that are recommended to be taken simultaneously

Subjects that continue the syllabus
/

Other comments

Recommendations to pass the course: Regular attendance to classes is recommended and resolve questions that arise during the study of the subject. It is important that the student read the literature recommended by teachers prior to the development of each seminar session. Performance of a work under the direct guidance of teachers through attendance at sessions of personalized attention.&nbsp;


(*)The teaching guide is the document in which the URV publishes the information about all its courses. It is a public document and cannot be modified. Only in exceptional cases can it be revised by the competent agent or duly revised so that it is in line with current legislation.