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Teaching GuideTerm Faculty of Science |
| Mestrado Universitario en Bioloxía Molecular , Celular e Xenética |
 Subjects |
| Human Genetics |
| Contents |
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| Identifying Data | 2018/19 | |||||||||||||
| Subject | Human Genetics | Code | 610441016 | |||||||||||
| Study programme |
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| Descriptors | Cycle | Period | Year | Type | Credits | |||||||||
| Official Master's Degree | 2nd four-month period |
First | Optional | 3 | ||||||||||
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| Topic | Sub-topic |
| Lecture 1. THE HUMAN GENOME: SEQUENCE AND VARIATION | Functional elements Protein-coding genes Non-coding, RNA-only genes Repetitive elements Mitochondrial genome Genomic variability Epigenetics |
| LECTURE 3. CHROMOSOMES AND CLINICAL SYNDROMES | The human karyotype Mitotic and meiotic alterations: non-disyunction Changes in Number and structure of the chromosomes Mosaics |
| LECTURE 4. MODES OF INHERITANCE | Familiar studies Mendelian inheritance Multiple alleles Complex inheritance Anticipation, expressivity, penetrance, mosaicism, mitochondrial inheritance and dynamic mutations |
| TEMA 4. ENFERMEDADES POLIXÉNICAS E MULTIFACTORIAIS. | Polixenes e variacións no fenotipo. Heredabilidade. |
| LECTURE 5. GENES AND CANCER. | Oncogenes and tumor supressor genes Germline mutations: familiar cancer Somatic cancer genetics |
| LECTURE 6. GENE THERAPY | Somatic and germinal gene therapy. Gene therapy vectors and nonviral vectors Ex vivo and in vivo methods. |
| LABORATORY PRACTICES | 1. The human karyotype and the identification of chromosome alterations. 2. Bioinformatics: search and comparison of DNA sequences. Databases and genome browsers |
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