Teaching GuideTerm
Faculty of Science
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Mestrado en Investigación Química e Química Industrial
 Subjects
  Química de Biomoléculas
   Contents
Topic Sub-topic
Chapter 1. Introduction and historical aspects. Basic structure and functions of cells. Most important biomolecules Different components of the cell. Organization. Structure and function of main biomolecules
CHAPTER 2. Peptides and proteins. Structural aspects. Synthesis and modification. Design of functional proteins. Metalloproteins: types, methods of study, examples and applications Amino acids and peptides. Proteins and functions. Primary, secondary, tertiary and quaternary structure. Biosynthesis. Chemical synthesis. Modification by chemical methods. Metalloproteins and synthetic models. Applications.
CHAPTER 3. Nucleic acids. Structural aspects. Synthesis and analysis techniques. Interactions with other nucleic acids. Interactions with small molecules. Interactions with metals. Interactions with proteins and peptides Structure of nucleotides. Structure and function of the different nucleic acids. Supramolecular chemistry of nucleic acids. Biosynthesis. Synthesis and manipulation of nucleic acids by chemical methods. Interaction with small molecules, proteins and metal complexes
CHAPTER 4. Carbohydrates and their derivatives. Structural and synthesis. Glycoconjugates and its role in cellular communication. Glycocode. Glycotherapy Monosaccharides, nomenclature, structure and chemistry. Oligosaccharides and polysaccharides, nomenclature, structure. Structural determination of oligo-and polysaccharides. Biosynthesis, chemical synthesis and biological synthesis of oligosaccharides. Glycosides and glycosidase inhibitors: types, incidence in nature, methods of synthesis and biological applications. Glycolipids. Types of structures. Natural incidence. Biosynthesis. Functions. Glycoproteins. Types of structures. Natural incidence. Biosynthesis. Functions. The glycocode concept. Future prospects and scope thereof. Glycotherapy and Glycoconjugates known functions.
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