This subject deals with quantifying substances in different types of samples at trace levels. The most common methodologies will be presented, along with their usual problems, difficulties and limitations when applying them. Major emphasis will be placed on how to plan and execute the different stages of the so-called ‘analytical process’. Options to automate several working steps will be discussed. Finally, some basic tools to treat the final data sets will be studied. This is termed chemometrics and it deals with experimental design and optimization of an analytical procedure, calibration and multivariate analyses of the data (including data mining).
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Subjects
