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Teaching GuideTerm Faculty of Science |
| Grao en Química |
 Subjects |
| Organic Chemistry 1 |
| Contents |
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| Identifying Data | 2017/18 | |||||||||||||
| Subject | Organic Chemistry 1 | Code | 610G01026 | |||||||||||
| Study programme |
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| Descriptors | Cycle | Period | Year | Type | Credits | |||||||||
| Graduate | 1st four-month period |
Second | Obligatoria | 6 | ||||||||||
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| Topic | Sub-topic |
| Unit 1. Organic reactions | Chemistry of the organic compounds: acids and bases, oxidants and reductors, electrophilicity and nucleophilicity. Reaction mechanisms: classification. Thermodynamic and kinetic features of Organic Reactions. Kinetic and thermodynamic control. Reaction intermediates. |
| Unit 2. Alkanes and cycloalkanes | Structural and physical properties. Rotational barriers. Conformational isomerism. Ring strain. |
| Unit 3. Stereochemistry | Optical activity. Chirality. Enantiomers and diasteroisomers: Nomenclature. Stereoisomerism in cyclic molecules. |
| Unit 4. NMR Spectroscopy | Basic principles of the NMR. The most important nuclei studied in Organic Chemistry. Chemical shift, Spin-spin coupling: N+1 rule. Identification of Organic functional groups by NMR. |
| Unit 5. Alkyl Halides | Structure and properties. Nomenclature. NMR spectroscopic properties. Nucleophilic substition reactions (SN): substrate (structure of the alkyl group and nature of the leaving group, nucleophilicity of the reagent and solvent effects. Competitive proccesses in the SN reaction: transpositions and eliminations. Organometallic compounds. Reduction of alkyl halides. |
| Unit 6. Alcohols | Nomenclature, structure and phisical properties. Acid-base character. Reactions through the O-H bond. Reactions through the C-O bond. Oxidation. Thiols. |
| Unit 7. Ethers | Chemical structure. Ether cleavage. Epoxides. Thioethers. |
| Unit 8. Amines | Structure and properties. Acid-base reactions. Alkylation of amines. Hoffman's elimination. Oxidation: Cope's elimination. |
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